CAJ | 학술논문

目的观察地佐辛超前镇痛在妇科腹腔镜手术中的作用与效果.方法 40例美国麻醉医师协会( ASA)分级Ⅰ～Ⅱ级拟行腹腔镜手术的患者,采用随机数字表法随机分为两组(每组20例),地佐辛超前镇痛组(A组)、地佐辛常规镇痛组(B组).A组于手术切皮前15 min静脉注射地佐辛10 mg,B组于手术结束前15 min静脉注射地佐辛10 mg.于术后2、4、8、12、24h随访并记录视觉模拟评分(VAS评分)、副作用发生情况.结果 A组术后2、4、8、12、24h各时点VAS评分[(1.7±0.6)、(1.5±0.5)、(1.2±0.5)、(4.1±0.9)、(1.2±0.4)低于同时点B组[(2.9±1.3)、(2.8±1.7)、(3.0±2.3)、(4.2±0.8)、(1.8±0.7)](P＜0.05),两组患者的不良反应发生率无统计学差异(P＞0.05). 结论地佐辛超前镇痛能有效减轻妇科腹腔镜手术患者的术后疼痛,且不增加术后副作用的发生率.
목적 관찰지좌신초전진통재부과복강경수술중적작용여효과.방법 40례미국마취의사협회( ASA)분급Ⅰ～Ⅱ급의행복강경수술적환자,채용수궤수자표법수궤분위량조(매조20례),지좌신초전진통조(A조)、지좌신상규진통조(B조).A조우수술절피전15 min정맥주사지좌신10 mg,B조우수술결속전15 min정맥주사지좌신10 mg.우술후2、4、8、12、24h수방병기록시각모의평분(VAS평분)、부작용발생정황.결과 A조술후2、4、8、12、24h각시점VAS평분[(1.7±0.6)、(1.5±0.5)、(1.2±0.5)、(4.1±0.9)、(1.2±0.4)저우동시점B조[(2.9±1.3)、(2.8±1.7)、(3.0±2.3)、(4.2±0.8)、(1.8±0.7)](P＜0.05),량조환자적불량반응발생솔무통계학차이(P＞0.05). 결론 지좌신초전진통능유효감경부과복강경수술환자적술후동통,차불증가술후부작용적발생솔.
Objective To observe the preemptive analgesic effect of dezocine on gynecological laparoscopy. Methods Forty patients(ASA Ⅰ -Ⅱ )were randomly assigned into two groups.The patients in group A(n=20) received intravenous injection of dezocine 10 mg 15 min before surgery,and those in group B (n=20) intravenous injection of dezocine 10 mg 15 min before the end of surgery.Postoperative analgesia efficacy was assessed by visual analog scales(VAS) at 2,4,8,12 and 24 h after surgery.Analgesic therapy and adverse effects were evaluated after surgery. Results VAS was lower in the group A[(1.7±0.6),(1.5±0.5),(1.2±0.5),(4.1±0.9),(1.2±0.4)] at 2,4,8,12,24 h (P＜0.05) than that in group B [(2.9:±1.3),(2.8±1.7),(3.0±.2.3),(4.2±0.8),(1.8±0.7)].There was no significant difference between the two groups in adverse effects (P＞0.05). Conclusions Dezocine for preemptive analgesia can effectively relieve postoperative pain in patients with gynecological laparoscopy,and can not increase the incidence of adverse effects.