CAJ | 학술논문

目的检测白细胞介素18(IL-18)和抵抗素在早产妊娠妇女血清中的含量,以探讨上述指标预测宫内感染的价值.方法选取早产妊娠妇女43例作为宫内感染组,选取同期进行产前检查的健康妊娠妇女40例作为对照组.分别抽取空腹静脉血进行IL-18和抵抗素含量的检测.结果宫内感染组IL-18的含量[(38.7±10.4)μg/L]高于对照组[(23.5±5.6)μg/L],差异有统计学意义(P＜0.01);宫内感染组抵抗素的含量[(24.84±5.32)μg/L]高于对照组[(17.32±5.15)μg/L],差异有统计学意义(P＜0.01);IL-18和抵抗素呈正相关关系(r=0.61,P＜0.01).结论 IL-18和抵抗素的含量在宫内感染的妊娠妇女中存在显著性变化,可作为预测宫内感染的辅助诊断指标.
목적 검측백세포개소18(IL-18)화저항소재조산임신부녀혈청중적함량,이탐토상술지표예측궁내감염적개치.방법 선취조산임신부녀43례작위궁내감염조,선취동기진행산전검사적건강임신부녀40례작위대조조.분별추취공복정맥혈진행IL-18화저항소함량적검측.결과 궁내감염조IL-18적함량[(38.7±10.4)μg/L]고우대조조[(23.5±5.6)μg/L],차이유통계학의의(P＜0.01);궁내감염조저항소적함량[(24.84±5.32)μg/L]고우대조조[(17.32±5.15)μg/L],차이유통계학의의(P＜0.01);IL-18화저항소정정상관관계(r=0.61,P＜0.01).결론 IL-18화저항소적함량재궁내감염적임신부녀중존재현저성변화,가작위예측궁내감염적보조진단지표.
Objective To study the relationships between serum intedeukin-18(IL-18)and resistin for predicting intraamniotic infection.Method Serum levels of IL-18 and resistin were measured in 43 pregnant women with intraamniotic infection (infection group)and 40 normal pregnant women(control group).Results The level of IL-18 in infection group[(38.7±10.4)μg/L]was higher than that in control group [(23.5±5.6)μg/L],there was significant difference between two groups (P＜0.01).The level of resistin in infection group[(24.84±5.32)μg/L]was higher than that in control group[(17.3±5.15) μg/L],there was significant difference between two groups(P＜0.01).The levels of resistin and IL-18 were correlated in pregnant women with intraamniotic infection(r=0.61,P＜0.01).Conclusion Detecting the levels of IL-18 and resistin in pregnant women can identify intramnniotic infection.