国际流行病学传染病学杂志
國際流行病學傳染病學雜誌
국제류행병학전염병학잡지
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY AND INFECTIOUS DISEASE
2012年
2期
80-83
,共4页
张国丽%苏慧勇%周俊%杨磊
張國麗%囌慧勇%週俊%楊磊
장국려%소혜용%주준%양뢰
老年人%艾滋病%临床特点
老年人%艾滋病%臨床特點
노년인%애자병%림상특점
Aged%AIDS%Clinical features
目的 探讨老年艾滋病患者的临床特点.方法 对58例年龄≥60岁的老年艾滋病患者的临床资料进行回顾性分析.结果 58例老年艾滋病患者中,男性48例(82.76％)、女性10例(17.24％).异性性传播52例(89.66％),1例有输血史,其余感染原因不明.临床表现以发热(34例)、咳嗽(32例)、乏力(31例)多见.CD4+T细胞计数7～ 437个/μL,平均CD4+T细胞计数149.6个/μL.并发机会性感染56例(96.56％),其中二重或多重感染41例(70.69％),呼吸系统感染最常见,共39例(67.24％),消化系统感染23例,血液系统感染5例.18例接受HAART 6个月,10例病毒载量＜400拷贝/mL,13例CD4+T细胞升高,平均147个/μL.住院期间死亡3例(5.17％).结论 老年HIV感染以异性性传播为主,可出现各种机会性感染,合并症复杂,二重或多重机会性感染多见,因此应充分重视对老年艾滋病的预防和治疗.HAART可有效抑制病毒的复制,使细胞免疫CD4+T细胞升高,改善患者的生活质量.
目的 探討老年艾滋病患者的臨床特點.方法 對58例年齡≥60歲的老年艾滋病患者的臨床資料進行迴顧性分析.結果 58例老年艾滋病患者中,男性48例(82.76％)、女性10例(17.24％).異性性傳播52例(89.66％),1例有輸血史,其餘感染原因不明.臨床錶現以髮熱(34例)、咳嗽(32例)、乏力(31例)多見.CD4+T細胞計數7～ 437箇/μL,平均CD4+T細胞計數149.6箇/μL.併髮機會性感染56例(96.56％),其中二重或多重感染41例(70.69％),呼吸繫統感染最常見,共39例(67.24％),消化繫統感染23例,血液繫統感染5例.18例接受HAART 6箇月,10例病毒載量＜400拷貝/mL,13例CD4+T細胞升高,平均147箇/μL.住院期間死亡3例(5.17％).結論 老年HIV感染以異性性傳播為主,可齣現各種機會性感染,閤併癥複雜,二重或多重機會性感染多見,因此應充分重視對老年艾滋病的預防和治療.HAART可有效抑製病毒的複製,使細胞免疫CD4+T細胞升高,改善患者的生活質量.
목적 탐토노년애자병환자적림상특점.방법 대58례년령≥60세적노년애자병환자적림상자료진행회고성분석.결과 58례노년애자병환자중,남성48례(82.76％)、녀성10례(17.24％).이성성전파52례(89.66％),1례유수혈사,기여감염원인불명.림상표현이발열(34례)、해수(32례)、핍력(31례)다견.CD4+T세포계수7～ 437개/μL,평균CD4+T세포계수149.6개/μL.병발궤회성감염56례(96.56％),기중이중혹다중감염41례(70.69％),호흡계통감염최상견,공39례(67.24％),소화계통감염23례,혈액계통감염5례.18례접수HAART 6개월,10례병독재량＜400고패/mL,13례CD4+T세포승고,평균147개/μL.주원기간사망3례(5.17％).결론 노년HIV감염이이성성전파위주,가출현각충궤회성감염,합병증복잡,이중혹다중궤회성감염다견,인차응충분중시대노년애자병적예방화치료.HAART가유효억제병독적복제,사세포면역CD4+T세포승고,개선환자적생활질량.
Objective To study the clinical features of older HIV/AIDS patients.Methods Clinical data of 58 HIV/AIDS cases whose age were over or equal to 60 years were analyzed retrospectively.Results Among 58 cases,48 were males ( 82.76 ％ ) and 10 were females ( 17.24 ％ ).Of all the cases,52 ( 89.66 ％ ) were heterosexual transmission,1 has blood transfusion history and others with unknown cause.Clinical manifestations were 34 patients fever,32 patients cough,31 patients fatigue.CD4 + T-lymphocyte counts were 7-437 cells/μL,average CD4 + T-lymphocyte counts were 149.6 cells/μL.Fifty-six cases were with opportunistic infections(96.56％ ),including double or multiple infection in 41 cases(70.69％ )..Respiratory infection was most frequently,there were 39 cases(67.24％) in total.Twenty-three cases were with digestive infection,5 patients with blood system infection.Eighteen patients were given HAART for 6 months,viral load in 10 cases decreased to lower than 400 copies/mL and CD4+ cell in 13 cases increased( 147 cells/μL).Three patients(5.17％) died during hospitalization.Conclusions The HIV infection for older people is mainly through heterosexual sex,these patients all have different opportunistic infection with complications complex,double or multiple opportunistic infections more common,so it is necessary to strengthen prevention and treatment for these patients.HAART can control the HIV infection effectively,increase the cellular immune CD4 + T-lymphocyte and improve the quality of life of the patients.
