CAJ | 학술논문

目的评价罗库溴铵对丙泊酚麻醉诱导气管插管时熵指数的影响.方法丙泊酚靶控输注麻醉诱导患者40例,随机分为0.6mg/kg罗库溴铵组(R组)和0.9%NaCl溶液组(S组),每组各20例.麻醉诱导2～3 min后快速气管插管.记录麻醉诱导前(Ta)和诱导后(Tb)、静脉注射罗库溴铵或0.9%NaCl溶液后2min(Tc)、气管插管后即刻(T)、气管插管后1、2和3min(T1、T2、T3)时反应熵(RE)和状态熵(SE).结果T2时S组RE-SE高于R组.气管插管可致RE和SE升高.与T0比较.R组和S组在T2时SE分别由50±8降至42±7和55±12降至43±13,RE由54±9降至45±6和66±15降至48±16(P<0.05).T0时S组RE和RE-SE明显升高.结论罗库溴铵影响RE-SE以及RE和RE-SE对气管插管的反应,神经肌肉阻滞药物可能会干扰气管插管时熵指数的监测.
목적 평개라고추안대병박분마취유도기관삽관시적지수적영향.방법 병박분파공수주마취유도환자40례,수궤분위0.6mg/kg라고추안조(R조)화0.9%NaCl용액조(S조),매조각20례.마취유도2～3 min후쾌속기관삽관.기록마취유도전(Ta)화유도후(Tb)、정맥주사라고추안혹0.9%NaCl용액후2min(Tc)、기관삽관후즉각(T)、기관삽관후1、2화3min(T1、T2、T3)시반응적(RE)화상태적(SE).결과T2시S조RE-SE고우R조.기관삽관가치RE화SE승고.여T0비교.R조화S조재T2시SE분별유50±8강지42±7화55±12강지43±13,RE유54±9강지45±6화66±15강지48±16(P<0.05).T0시S조RE화RE-SE명현승고.결론 라고추안영향RE-SE이급RE화RE-SE대기관삽관적반응,신경기육조체약물가능회간우기관삽관시적지수적감측.
Objective To evaluate the effect of rocuronium on entropy to endotracheal intubation during anesthesia induction with propofol. Methods Forty patients anesthetized induction with propofol using a target-controlled infusion were randomly divided into two groups: rocuronium group (R group, 20 cases) received 0.6 mg/kg rocuronium or saline group (S group, 20 cases) received saline. 2-3 min later, endotracheal intubation was performed. Response entropy(RE) and state entropy(SE) were recorded during baseline(Ta), at steady state(Tb), 2 min after rocuro nium or saline administration (Tc) and 0, 1, 2 and 3 min after endotracheal intubation (T0, T1, T2, T3). Results At T2, the RE-SE was higher in S group than that in R group. Endotracheal intubation induced increasing in RE and SE. Comparing T2 and T0 values in R group and S group, SE increased from 42 ± 7 to 50 ± 8 and 43 ± 13 to 55 ± 12, and RE increased from 45 ± 6 to 54 ± 9 and 48 ± 16 to 66 ± 15, respectively. At T0, RE and RE-SE were higher in S group. Conclusion Rocuronium affects RE-SE and RE and RE-SE responses to endotracheal intubation and may confound interpretation of entropy monitoring.