中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2008年
2期
145-146
,共2页
施亚雄%周竞雄%李永加%陶耕
施亞雄%週競雄%李永加%陶耕
시아웅%주경웅%리영가%도경
格列齐特%糖尿病%2型%血糖波动%自我血糖监测
格列齊特%糖尿病%2型%血糖波動%自我血糖鑑測
격렬제특%당뇨병%2형%혈당파동%자아혈당감측
Gliclazide%Diabetes mellitus%type 2%Blood glucose excursion%Self-monitor blood glucose
123例2型糖尿病患者分为格列齐特缓释片(达美康(R)MR)组、格列齐特(达美康(R))组、格列本脲组,治疗16周,同时自我血糖监测 (SMBG).3组降糖效果相似.但反映血糖波动的最高血糖最低血糖差值、反映餐后血糖波动的全天平均餐后最高血糖、餐后2 h血糖、餐后2 h胰岛素和低血糖事件,格列齐特缓释片组均明显低于格列本脲组(均P<0.01).提示SMBG是评估血糖波动的实用方法.
123例2型糖尿病患者分為格列齊特緩釋片(達美康(R)MR)組、格列齊特(達美康(R))組、格列本脲組,治療16週,同時自我血糖鑑測 (SMBG).3組降糖效果相似.但反映血糖波動的最高血糖最低血糖差值、反映餐後血糖波動的全天平均餐後最高血糖、餐後2 h血糖、餐後2 h胰島素和低血糖事件,格列齊特緩釋片組均明顯低于格列本脲組(均P<0.01).提示SMBG是評估血糖波動的實用方法.
123례2형당뇨병환자분위격렬제특완석편(체미강(R)MR)조、격렬제특(체미강(R))조、격렬본뇨조,치료16주,동시자아혈당감측 (SMBG).3조강당효과상사.단반영혈당파동적최고혈당최저혈당차치、반영찬후혈당파동적전천평균찬후최고혈당、찬후2 h혈당、찬후2 h이도소화저혈당사건,격렬제특완석편조균명현저우격렬본뇨조(균P<0.01).제시SMBG시평고혈당파동적실용방법.
A total of 123 type 2 diabetics was randomised into 3 groups to receive gliclazide-MR, gliclazide or glibenclamide treatments for 16 weeks.All the subjects took self-monitoring of blood glucose (SMBG) during the trial.The effect of therapy was similar in 3 groups.The subtraction value between maximum and minimum blood glucose, mean postprandial maximum blood glucose, postprandial 2 h blood glucose, postprandial 2 h serum insulin and hypoglycaemia events were lower in gliclazide-MR group than those in glibenclamide group (all P<0.01).The data suggest that SMBG is an useful method to evaluate blood glucose excursion.