中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2010年
3期
241-244
,共4页
马靖%冯洁%吕泽平%黄慧%万刚%黄金%张建佚%杨双雨%杜建玲%郭立新%杨泽
馬靖%馮潔%呂澤平%黃慧%萬剛%黃金%張建佚%楊雙雨%杜建玲%郭立新%楊澤
마정%풍길%려택평%황혜%만강%황금%장건일%양쌍우%두건령%곽립신%양택
代谢综合征%糖尿病%空腹血糖调节受损%患病风险
代謝綜閤徵%糖尿病%空腹血糖調節受損%患病風險
대사종합정%당뇨병%공복혈당조절수손%환병풍험
Metabolic syndrome%Diabetes mellitus%Impaired fasting glycaemia%Risk of diabetes mellitus
目的 探讨年龄对正常人群及代谢综合征(MS)患者糖尿病患病风险的影响.方法 按照随机抽样原则,选取北京地区年龄在20岁以上、录入资料完整的8280人作为研究对象(男性4873人,女性3407人).将总体人群分为正常人群组和MS患者组,并以年龄每10岁为组距对研究对象进行年龄分组,分别计算各组血糖正常者、空腹血糖调节受损(IFG)和糖尿病(DM)患者的人数及其构成比.结果 (1)总体人群、正常人群和MS患者各自的不同年龄组IFG及DM患病风险不同(P<0.05);(2)总体人群中IFG患病率随年龄递增,DM患病率在20-79岁人群中随年龄递增,80岁以上人群中降低,经趋势X~2检验,P<0.05;(3)正常人群中IFG患病率与DM患病率均在20-79岁人群中随年龄递增,80岁以上人群中降低;(4)MS患者中IFG患病率在20-69岁人群中随年龄递增,70岁及以上人群中降低,DM患病率未见随年龄变化趋势.结论 (1)在正常人群中IFG和DM患病率随年龄增加,年龄越大,患病人数越多,表现出高龄群体高患病风险的增龄特点;(2)MS患者中IFG亦表现出增龄特点,但是DM的患病风险与年龄无关;(3)无论是否伴有MS,70-79岁年龄段均为DM的高患病风险阶段.
目的 探討年齡對正常人群及代謝綜閤徵(MS)患者糖尿病患病風險的影響.方法 按照隨機抽樣原則,選取北京地區年齡在20歲以上、錄入資料完整的8280人作為研究對象(男性4873人,女性3407人).將總體人群分為正常人群組和MS患者組,併以年齡每10歲為組距對研究對象進行年齡分組,分彆計算各組血糖正常者、空腹血糖調節受損(IFG)和糖尿病(DM)患者的人數及其構成比.結果 (1)總體人群、正常人群和MS患者各自的不同年齡組IFG及DM患病風險不同(P<0.05);(2)總體人群中IFG患病率隨年齡遞增,DM患病率在20-79歲人群中隨年齡遞增,80歲以上人群中降低,經趨勢X~2檢驗,P<0.05;(3)正常人群中IFG患病率與DM患病率均在20-79歲人群中隨年齡遞增,80歲以上人群中降低;(4)MS患者中IFG患病率在20-69歲人群中隨年齡遞增,70歲及以上人群中降低,DM患病率未見隨年齡變化趨勢.結論 (1)在正常人群中IFG和DM患病率隨年齡增加,年齡越大,患病人數越多,錶現齣高齡群體高患病風險的增齡特點;(2)MS患者中IFG亦錶現齣增齡特點,但是DM的患病風險與年齡無關;(3)無論是否伴有MS,70-79歲年齡段均為DM的高患病風險階段.
목적 탐토년령대정상인군급대사종합정(MS)환자당뇨병환병풍험적영향.방법 안조수궤추양원칙,선취북경지구년령재20세이상、록입자료완정적8280인작위연구대상(남성4873인,녀성3407인).장총체인군분위정상인군조화MS환자조,병이년령매10세위조거대연구대상진행년령분조,분별계산각조혈당정상자、공복혈당조절수손(IFG)화당뇨병(DM)환자적인수급기구성비.결과 (1)총체인군、정상인군화MS환자각자적불동년령조IFG급DM환병풍험불동(P<0.05);(2)총체인군중IFG환병솔수년령체증,DM환병솔재20-79세인군중수년령체증,80세이상인군중강저,경추세X~2검험,P<0.05;(3)정상인군중IFG환병솔여DM환병솔균재20-79세인군중수년령체증,80세이상인군중강저;(4)MS환자중IFG환병솔재20-69세인군중수년령체증,70세급이상인군중강저,DM환병솔미견수년령변화추세.결론 (1)재정상인군중IFG화DM환병솔수년령증가,년령월대,환병인수월다,표현출고령군체고환병풍험적증령특점;(2)MS환자중IFG역표현출증령특점,단시DM적환병풍험여년령무관;(3)무론시부반유MS,70-79세년령단균위DM적고환병풍험계단.
Objective To investigate the impact of age on patients with metabolic syndrome (MS) and normal persons. Methods Data was gathered from 8280 persons including 4873 males and 3407 females who were randomly selected. All subjects were devided into normal group and MS group. According to the interval of ten years, the subjects were devided into seven age groups, to calculate the difference of impaired fasting glycaemia (IFG) between patients with diabetes mellitus (DM) and normal people, as well as the related portions. Results (1) The risk of IFG and DM appeared to be different among age groups among the target subjects as well as in the normal and the MS groups (P<0.05). (2) Among the whole subjects, the overall prevalence of IFG was increasing with age. The prevalence of DM had an increasing trend with age augment in 20-79 years group, whereas a decreasing trend appeared in people over 80 years of age. (3) For normal persons, the prevalence of IFG and DM were all increasing with age augment in 20-79 years group, and then decreasing with age augment in the over-80-years group. (4)For MS patients, the prevalence of IFG had an increasing trend with age augment in 20-69 years group, whereas a decreasing trend appeared in people over 70 years of age. There was no tendency of variation with age augment in DM.Conclusions (1) For normal persons, high prevalence rates of IFG and DM were correlated to age augment, especially in senior persons. (2) For MS patients, high prevalence of IFG was also correlated to age augment, but no association between prevalence of DM and age augment was seen. (3)Age from 70 to 79 years appeared to be in high risk with MS.