北京大学学报(自然科学版)
北京大學學報(自然科學版)
북경대학학보(자연과학판)
ACTA SCIENTIARUM NATURALIUM UNIVERSITATIS PEKINENSIS
1999年
3期
317-327
,共11页
吴望一%温功碧%张子荣%王英晓%严宗毅
吳望一%溫功碧%張子榮%王英曉%嚴宗毅
오망일%온공벽%장자영%왕영효%엄종의
右心室%肺动脉%动态耦合%输入阻抗%轻微非对称T型管模型%分布参数
右心室%肺動脈%動態耦閤%輸入阻抗%輕微非對稱T型管模型%分佈參數
우심실%폐동맥%동태우합%수입조항%경미비대칭T형관모형%분포삼수
right ventricle%pulmonary arteries%dynamic coupling%input impedance%slight asymmetric T tube model%distributed parameters
根据肺循环血管系统的解剖结构,提出了模拟肺动脉输入阻抗的轻微非对称T型管模型.计算得到的肺动脉输入阻抗与实验数据比较表明,该模型能很好地模拟右心室的后负荷.还利用右心室的E(t)-R模型及肺动脉的轻微非对称T型管模型,应用脉冲响应法,对肺循环的动态耦合及心血管参数的影响进行了研究,发现了一个心动周期中,右心室对肺动脉压力和流量变化起主导作用.
根據肺循環血管繫統的解剖結構,提齣瞭模擬肺動脈輸入阻抗的輕微非對稱T型管模型.計算得到的肺動脈輸入阻抗與實驗數據比較錶明,該模型能很好地模擬右心室的後負荷.還利用右心室的E(t)-R模型及肺動脈的輕微非對稱T型管模型,應用脈遲響應法,對肺循環的動態耦閤及心血管參數的影響進行瞭研究,髮現瞭一箇心動週期中,右心室對肺動脈壓力和流量變化起主導作用.
근거폐순배혈관계통적해부결구,제출료모의폐동맥수입조항적경미비대칭T형관모형.계산득도적폐동맥수입조항여실험수거비교표명,해모형능흔호지모의우심실적후부하.환이용우심실적E(t)-R모형급폐동맥적경미비대칭T형관모형,응용맥충향응법,대폐순배적동태우합급심혈관삼수적영향진행료연구,발현료일개심동주기중,우심실대폐동맥압력화류량변화기주도작용.
Based on the anatomical structure of pulmonary arteries, a slightly asymmetric T-tube model with distributed parameters is proposed herein to simulate the pulmonary arteries. Comparison between our calculated input impedance to the pulmonary arteries with available experimental data proves that such a model provides an excellent simulation to the right ventricular afterload. With a E (t)-R model for the right ventricle and a slightly asymmetric T tube model for the pulmonary arteries, the dynamic coupling of the right ventricle and pulmonary circulation is quantitatively studied using the impulse response method. The influence of various cardiovascular parameters is discussed. It is found that the right ventricle plays a predominant role over the pulmonary arteries in determining the pulmonary blood pressure and flow variations during a cardiac cycle.