中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2012年
2期
106-108
,共3页
角膜磨镶术,激光原位%生物力学,角膜%角膜阻力因子%角膜滞后
角膜磨鑲術,激光原位%生物力學,角膜%角膜阻力因子%角膜滯後
각막마양술,격광원위%생물역학,각막%각막조력인자%각막체후
Keratomileusis,laser in situ%Biomechanics,corneal%Corneal resistance factor%Corneal hysteresis
目的 比较准分子激光原位角膜磨镶术( LASIK)前角膜阻力因子(CRF)和角膜滞后量(CH)与中央角膜厚度的关系；比较LASIK术前及术后不同时间段角膜的生物力学特性.方法 病例对照研究.选取2010年1月至2010年2月在山西省眼科医院要求行LASIK手术的近视患者84例(168眼).根据角膜厚度为分为A组(550～643 μm,67眼)、B组(500～549μm,72眼)、C组(450～499 μm,29眼),用眼反应分析仪(ORA)测定这些术眼的CRF和CH,并进行比较分析.对其中已手术并定期完成12个月随访有完整资料的40例(80眼)患者进行术前及术后不同时间段(术后1、3、6、12个月)角膜生物力学特性的比较分析.采用单因素方差分析法对数据进行统计.结果 术前三组的CRF和CH 分别为11.11±1.69和10.79±1.48、9.83±1.39和9.87±1.29、9.06±1.96和9.79±1.76,差异均有统计学意义(F=19.55、8.54,P＜0.01).40例患者术前及术后各时间段CRF与CH的差异均有统计学意义(F=102.88、60.80,P＜0.01).术后各时间段各组CRF与CH差异均无统计学意义.结论 CRF和CH与中央角膜厚度有关,随着角膜厚度的减小而降低.LASIK术后残留角膜基质床厚度为整个角膜厚度的50％以上时,角膜生物力学特性基本稳定,是安全的切削范围.
目的 比較準分子激光原位角膜磨鑲術( LASIK)前角膜阻力因子(CRF)和角膜滯後量(CH)與中央角膜厚度的關繫；比較LASIK術前及術後不同時間段角膜的生物力學特性.方法 病例對照研究.選取2010年1月至2010年2月在山西省眼科醫院要求行LASIK手術的近視患者84例(168眼).根據角膜厚度為分為A組(550～643 μm,67眼)、B組(500～549μm,72眼)、C組(450～499 μm,29眼),用眼反應分析儀(ORA)測定這些術眼的CRF和CH,併進行比較分析.對其中已手術併定期完成12箇月隨訪有完整資料的40例(80眼)患者進行術前及術後不同時間段(術後1、3、6、12箇月)角膜生物力學特性的比較分析.採用單因素方差分析法對數據進行統計.結果 術前三組的CRF和CH 分彆為11.11±1.69和10.79±1.48、9.83±1.39和9.87±1.29、9.06±1.96和9.79±1.76,差異均有統計學意義(F=19.55、8.54,P＜0.01).40例患者術前及術後各時間段CRF與CH的差異均有統計學意義(F=102.88、60.80,P＜0.01).術後各時間段各組CRF與CH差異均無統計學意義.結論 CRF和CH與中央角膜厚度有關,隨著角膜厚度的減小而降低.LASIK術後殘留角膜基質床厚度為整箇角膜厚度的50％以上時,角膜生物力學特性基本穩定,是安全的切削範圍.
목적 비교준분자격광원위각막마양술( LASIK)전각막조력인자(CRF)화각막체후량(CH)여중앙각막후도적관계；비교LASIK술전급술후불동시간단각막적생물역학특성.방법 병례대조연구.선취2010년1월지2010년2월재산서성안과의원요구행LASIK수술적근시환자84례(168안).근거각막후도위분위A조(550～643 μm,67안)、B조(500～549μm,72안)、C조(450～499 μm,29안),용안반응분석의(ORA)측정저사술안적CRF화CH,병진행비교분석.대기중이수술병정기완성12개월수방유완정자료적40례(80안)환자진행술전급술후불동시간단(술후1、3、6、12개월)각막생물역학특성적비교분석.채용단인소방차분석법대수거진행통계.결과 술전삼조적CRF화CH 분별위11.11±1.69화10.79±1.48、9.83±1.39화9.87±1.29、9.06±1.96화9.79±1.76,차이균유통계학의의(F=19.55、8.54,P＜0.01).40례환자술전급술후각시간단CRF여CH적차이균유통계학의의(F=102.88、60.80,P＜0.01).술후각시간단각조CRF여CH차이균무통계학의의.결론 CRF화CH여중앙각막후도유관,수착각막후도적감소이강저.LASIK술후잔류각막기질상후도위정개각막후도적50％이상시,각막생물역학특성기본은정,시안전적절삭범위.
Objective The aim of this study was to investigate the corneal resistance factor (CRF) and corneal hysteresis (CH) before laser in situ keratomileusis (LASIK) and to determine their relationship to central corneal thickness (CCT) and to compare the biomechanical properties of the preoperative and postoperative periods of LASIK surgery.Methods This was a case-control study.Eighty-four patients (168 eyes) were selected from January 2010 to February 2010 in Shanxi Eye Hospital who were scheduled to undergo LASIK surgery.CH and CRF values were compared to three corneal thicknesses (group A,550-643 μm; group B,500-549 μm; group C,450-499 μm).An Optical Reaction Analyzer (ORA) was used for measurements.Complete records were obtained from 40 patients (80 eyes) who visited regularly for 1 year and a comparative analysis of the corneal biomechanical characteristics were available for both the preoperative and postoperative periods (1,3,6, 1 months).A one-way ANOVA were used for data analysis using SPSS 13.0 software.Results The CRF and CH values for the three preoperative central corneal thickness groups were: 11.11±1.69 and 10.79±1.48, 9.83±1.39 and 9.87±1.29, 9.06±1.96 and 9.79±1.76. The differences were statistically significant (F=19.55,P＜0.01; F=8.54,P＜0.01).The differences in the CRF and CH values for the preoperative and postoperative periods were also statistically significant (F=102.88,P＜0.01; F=60.80, P＜0.01). But the CRF and CH values for the different postoperative periods were not statistically significant. Conclusion The CRF and CH values decreases with decreased corneal thickness. Corneal biomechanical characteristics are reduced significantly after LASIK surgery, but there is no change during the postoperative period after LASIK.More than 50％ of the entire corneal thickness is composed of the residual corneal stroma that is fairly stable and safe after LASIK.
