CAJ | 학술논문

目的提高临床诊断弥散性神经胶质瘤的水平。方法对4例神经胶质瘤病例的临床症状、体征、MRI进行分析，2例开颅手术，2例CT立体定向活检术，均经病理证实为弥散性神经胶质瘤病。结果 4例均有颅内压增高表现，除1例病灶累及大脑2个脑叶外，其余均累及大脑3个叶。病灶在T1W1均呈低或等信号，在T2W1上呈高信号。局部脑组织肿胀，无坏死囊变及出血，占位效应不明显，增强扫描无明显强化，3例胼胝体肥大增厚。结论 MRI有其特有表现。手术或立体定向活检术是确诊该病的最佳选择。确诊后化疗及放疗应作为常规治疗的手段。
목적제고림상진단미산성신경효질류적수평。방법대4례신경효질류병례적림상증상、체정、MRI진행분석，2례개로수술，2례CT입체정향활검술，균경병리증실위미산성신경효질류병。결과 4례균유로내압증고표현，제1례병조루급대뇌2개뇌협외，기여균루급대뇌3개협。병조재T1W1균정저혹등신호，재T2W1상정고신호。국부뇌조직종창，무배사낭변급출혈，점위효응불명현，증강소묘무명현강화，3례변지체비대증후。결론 MRI유기특유표현。수술혹입체정향활검술시학진해병적최가선택。학진후화료급방료응작위상규치료적수단。
Objective　To enhance the correctness in the diagnosis of diffuse neurogliomatosis.　Methods　Patients with diffuse neurogliomatosis were analyzed in terms of manifestations, signs, and MI images. Craniotomy was performed in 2 patients and stereotaxic biopsy in 2. The diagnosis was verified pathologically.　Results　Increased intracraniopressure was noted in all patients. Two brain lobes were involved in 1 patient, and 3 in others. MRI showed low or equal signal areas in T1W1, and high ones in T2W1. Brain edema was note without necrosis, cyst, and bleeding. MRI occupying effect was not significant, corpus callosum enlarged, and no enhancement demonstrated.　Conclusions　Diffuse neurogliomatosis has specific features on MRI. Craniotomy or stereotaxic biopsy was the best choice for diagnosis. Chemotherapy and radiotherapy should be used.