CAJ | 학술논문

目的评价经肝动脉灌注化疗与静脉化疗治疗结肠癌肝转移的疗效。方法 64例结肠癌肝转移患者随机分为肝动脉灌注化疗组和静脉化疗组。两组均采用FAM方案化疗。分析两组的CR、PR、RR及1、2、3年生存率。结果肝动脉灌注化疗组的CR、PR、RR显著高于静脉化疗组（20％ vs. 8.6％, 47.5% vs. 22.3％, 67.5％ vs. 31.7％, P<0.05）；肝动脉灌注化疗组的1、2、3年生存率也显著高于静脉化疗组（84.4％ vs. 21.9％, 59.4％ vs. 6.3％, 34.4％ vs. 0％, P<0.05）。结论肝动脉灌注化疗治疗结肠癌肝转移优于静脉化疗。
목적평개경간동맥관주화료여정맥화료치료결장암간전이적료효。방법 64례결장암간전이환자수궤분위간동맥관주화료조화정맥화료조。량조균채용FAM방안화료。분석량조적CR、PR、RR급1、2、3년생존솔。결과간동맥관주화료조적CR、PR、RR현저고우정맥화료조（20％ vs. 8.6％, 47.5% vs. 22.3％, 67.5％ vs. 31.7％, P<0.05）；간동맥관주화료조적1、2、3년생존솔야현저고우정맥화료조（84.4％ vs. 21.9％, 59.4％ vs. 6.3％, 34.4％ vs. 0％, P<0.05）。결론간동맥관주화료치료결장암간전이우우정맥화료。
Objective　To evaluate the therapeutic effect of hepatic arterial infusion and venous chemotherapy in the treatment of patients with liver metastases from colon cancer.Methods　Sixty-four patients with liver metastases from colon cancer were randomly divided into hepatic arterial infusion (HAI) group and venous chemotherapy (VC) group. FAM chemtherapy protocol was used in both two groups. CR, PR, RR and 1-, 2-, 3-year survival rates in two groups were analyzed.Results　CR, PR, RR in HAI group was significantly higher than that in VC group (20% vs. 8.6%; 47.5% vs. 22.3%; 67.5% vs. 31.7%, P<0.05, respectively). 1-,2-, and 3-year survival rates in HAI group were also significantly higher than those in VC group (84.4% vs. 21.9%; 59.4% vs. 6.3%; 34.4% vs. 0%, P<0.05, respectively).Conclusion　HAI was superior to VC group in the treatment of liver metastases from colon cancer.