CAJ | 학술논문

目的探讨赖诺普利、曲美他嗪对急性冠脉综合征合并2型糖尿病患者血管内皮功能及糖化血红蛋白的影响，及心脏事件发生情况。方法治疗组采用赖诺普利、曲美他嗪治疗，对照组采用传统方法治疗；在改善血管内皮功能、降低糖化血红蛋白、防治心血管事件等方面比较疗效。结果治疗组在改善血管内皮功能、降低糖化血红蛋白(7.0％vs.8.0％)、防治心血管事件（13例vs.23例）等方面优于对照组。结论赖诺普利、曲美他嗪对急性冠脉综合征合并2型糖尿病患者，可显著改善血管内皮功能、降低糖化血红蛋白、防治心血管事件，患者多方面受益。
목적 탐토뢰낙보리、곡미타진대급성관맥종합정합병2형당뇨병환자혈관내피공능급당화혈홍단백적영향，급심장사건발생정황。방법 치료조채용뢰낙보리、곡미타진치료，대조조채용전통방법치료；재개선혈관내피공능、강저당화혈홍단백、방치심혈관사건등방면비교료효。결과 치료조재개선혈관내피공능、강저당화혈홍단백(7.0％vs.8.0％)、방치심혈관사건（13례vs.23례）등방면우우대조조。결론 뢰낙보리、곡미타진대급성관맥종합정합병2형당뇨병환자，가현저개선혈관내피공능、강저당화혈홍단백、방치심혈관사건，환자다방면수익。
Objective To explore effects of lisinopril and trimetazidine treating acute coronary artery syndrome combined with 2-type diabetes mellitus, such as blood vessel endothelium function and glycosylated hemoglobin effect and heart blood vessel event of acute coronary artery syndrome combined with 2-type diabetes mellitus. Methods Therapy group offered lisinopril and trimetazidine, control group received traditional method, compared with curative effect of improving blood vessel endothelium function, depressing glycosylated hemoglobin, preventing and curing heart blood vessel event. Results Therapy group is better than control group in improving blood vessel endothelium function, depressing glycosylated hemoglobin, preventing and curing heart blood vessel event. Conclusion Lisinopril and trimetazidine can improve blood vessel endothelium function, depress glycosylated hemoglobin, prevent and cure heart blood vessel event of acute coronary artery syndrome combined wih 2-type diabetes mellitus.Patients can benefit from it in many ways.