中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2010年
9期
962-965
,共4页
陶相宜%石晶%郭淑玲%董志军%王跃丽%乔志艳%张铁民
陶相宜%石晶%郭淑玲%董誌軍%王躍麗%喬誌豔%張鐵民
도상의%석정%곽숙령%동지군%왕약려%교지염%장철민
视网膜分支静脉阻塞%黄斑水肿%激光光凝%多焦视网膜电图
視網膜分支靜脈阻塞%黃斑水腫%激光光凝%多焦視網膜電圖
시망막분지정맥조새%황반수종%격광광응%다초시망막전도
Branch retinal vein occlusion%Macular edema%Laser photocoagulation%Multifocal electroretinogram
目的 应用多焦视网膜电图(multifocal electroretinogram,mfERG)观察激光光凝对于视网膜颞上分支静脉阻塞所致黄斑水肿的疗效.方法 对视网膜颞上分支静脉阻塞合并黄斑水肿的病例,进行多焦视网膜电图检查,分析其一阶反应(FOK),N1、P1波振幅密度值及其潜伏期.结果 中心凹处P1波振幅密度在光凝治疗后3个月开始恢复,治疗后6个月明显升高,与光凝治疗前相比差异具有统计学意义(P＜0.05、P＜0.01);2环P1波潜伏期在光凝治疗后3个月比治疗前有所缩短(P＜0.05),到治疗后6个月时改善更加明显,与治疗前相比差异具有统计学意义(P＜0.01).颞上象限视网膜P1波振幅密度值在治疗后一个月与治疗前相比下降,其差异具有统计学意义(P＜0.05).结论 激光光凝可以有效治疗视网膜分支静脉阻塞所致的黄斑水肿,多焦视网膜电图在疗效评估方面具有重要价值,P1波振幅密度和P1波潜伏期可作为评价疗效的敏感指标.
目的 應用多焦視網膜電圖(multifocal electroretinogram,mfERG)觀察激光光凝對于視網膜顳上分支靜脈阻塞所緻黃斑水腫的療效.方法 對視網膜顳上分支靜脈阻塞閤併黃斑水腫的病例,進行多焦視網膜電圖檢查,分析其一階反應(FOK),N1、P1波振幅密度值及其潛伏期.結果 中心凹處P1波振幅密度在光凝治療後3箇月開始恢複,治療後6箇月明顯升高,與光凝治療前相比差異具有統計學意義(P＜0.05、P＜0.01);2環P1波潛伏期在光凝治療後3箇月比治療前有所縮短(P＜0.05),到治療後6箇月時改善更加明顯,與治療前相比差異具有統計學意義(P＜0.01).顳上象限視網膜P1波振幅密度值在治療後一箇月與治療前相比下降,其差異具有統計學意義(P＜0.05).結論 激光光凝可以有效治療視網膜分支靜脈阻塞所緻的黃斑水腫,多焦視網膜電圖在療效評估方麵具有重要價值,P1波振幅密度和P1波潛伏期可作為評價療效的敏感指標.
목적 응용다초시망막전도(multifocal electroretinogram,mfERG)관찰격광광응대우시망막섭상분지정맥조새소치황반수종적료효.방법 대시망막섭상분지정맥조새합병황반수종적병례,진행다초시망막전도검사,분석기일계반응(FOK),N1、P1파진폭밀도치급기잠복기.결과 중심요처P1파진폭밀도재광응치료후3개월개시회복,치료후6개월명현승고,여광응치료전상비차이구유통계학의의(P＜0.05、P＜0.01);2배P1파잠복기재광응치료후3개월비치료전유소축단(P＜0.05),도치료후6개월시개선경가명현,여치료전상비차이구유통계학의의(P＜0.01).섭상상한시망막P1파진폭밀도치재치료후일개월여치료전상비하강,기차이구유통계학의의(P＜0.05).결론 격광광응가이유효치료시망막분지정맥조새소치적황반수종,다초시망막전도재료효평고방면구유중요개치,P1파진폭밀도화P1파잠복기가작위평개료효적민감지표.
Objective To observe the therapeutic efficacy of laser photocoagulation for macular edema secondary to superior temporal branch retinal vein occlusion determined by multifocal electroretinogram.Methods Implemented multifocal electroretinogram examination to the patients with macular edema secamplitude densities and latencies ofN1-wave, P1-wave. Results The amplitude density of P1-wave in fovea began to improve at the 3rd month post-treatment and the improvement was more obvious at the 6th month post-treatment with statistically significance (P＜0.05, P＜0.01). The latency of P1-wave in ring 2 shortened at the 3rd month post-treatment and the improvement was more obvious at the 6th month post-treatment with statistically significance (P＜0.05, P＜0.01). Compared with pre-treatment value, the amplitude density of P1-wave in superior temporal retina decreased at the 1st month post-treatment with statistically significance (P＜0.05).Conclusions Laser photocoagulation can alleviate the macular edema secondary to branch retinal vein occlusion. Multifocal electroretinogram technique has the significant value to evaluate the therapeutic efficacy. The amplitude density and latency of P1-wave may be regarded as sensitive estimate indexes.
