肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2010年
4期
222-224
,共3页
郭智%陈丰%马德彰%何学鹏%陈惠仁%张育葵%胡碧川%纪妍%瞿嵘
郭智%陳豐%馬德彰%何學鵬%陳惠仁%張育葵%鬍碧川%紀妍%瞿嶸
곽지%진봉%마덕창%하학붕%진혜인%장육규%호벽천%기연%구영
孤立性浆细胞瘤%临床分析%治疗%随访%回顾性研究
孤立性漿細胞瘤%臨床分析%治療%隨訪%迴顧性研究
고립성장세포류%림상분석%치료%수방%회고성연구
Solitary bone plasmacytomas%Clinical analysis%Therapy%Follow-up%Retrospective studies
目的 通过总结分析骨孤立性浆细胞瘤(SBP)的临床特点及治疗方法来提高其诊治水平.方法 回顾分析5家医院1999年至2009年收治的18例SBP的临床资料,对其临床特点及治疗疗效进行总结.结果 18例SBP患者年龄35～78岁,平均年龄54.2岁,男女比2.6∶1.通过随访治疗1～10年,采用化放疗治疗的10例患者有8例生存,2例死于进展为多发性骨髓瘤(MM),单纯化疗或单纯放疗的8例患者中有1例因化疗相关并发症死亡,2例死于进展为MM.全部患者目前共有11例处于持续缓解状态(CCS),2例因进展为MM在积极治疗中,平均CCS时间为47.3个月.结论 SBP是低度恶性肿瘤,化疗和放疗是其治疗的主要手段,化放疗相结合预后满意,部分患者可转化为MM.
目的 通過總結分析骨孤立性漿細胞瘤(SBP)的臨床特點及治療方法來提高其診治水平.方法 迴顧分析5傢醫院1999年至2009年收治的18例SBP的臨床資料,對其臨床特點及治療療效進行總結.結果 18例SBP患者年齡35～78歲,平均年齡54.2歲,男女比2.6∶1.通過隨訪治療1～10年,採用化放療治療的10例患者有8例生存,2例死于進展為多髮性骨髓瘤(MM),單純化療或單純放療的8例患者中有1例因化療相關併髮癥死亡,2例死于進展為MM.全部患者目前共有11例處于持續緩解狀態(CCS),2例因進展為MM在積極治療中,平均CCS時間為47.3箇月.結論 SBP是低度噁性腫瘤,化療和放療是其治療的主要手段,化放療相結閤預後滿意,部分患者可轉化為MM.
목적 통과총결분석골고립성장세포류(SBP)적림상특점급치료방법래제고기진치수평.방법 회고분석5가의원1999년지2009년수치적18례SBP적림상자료,대기림상특점급치료료효진행총결.결과 18례SBP환자년령35～78세,평균년령54.2세,남녀비2.6∶1.통과수방치료1～10년,채용화방료치료적10례환자유8례생존,2례사우진전위다발성골수류(MM),단순화료혹단순방료적8례환자중유1례인화료상관병발증사망,2례사우진전위MM.전부환자목전공유11례처우지속완해상태(CCS),2례인진전위MM재적겁치료중,평균CCS시간위47.3개월.결론 SBP시저도악성종류,화료화방료시기치료적주요수단,화방료상결합예후만의,부분환자가전화위MM.
Objective To improve the diagnosis level of solitary bone plasmacytoma (SBP) through analysing the clinical characteristics and therapy of this disease. Methods The clinical data of 18 cases were retrospectively analysis since 1999 in five hospitals, the clinical characteristics and therapeutic effect was summarized. Results The average age of 18 cases is 54.2 year (35-78), male were 1.6 times than female. 8 of 10 patients survived for 1-10 year after chemoradiotherapy, 2 of them progressed to multiple myeloma (MM)and died. 5 of 8 patients survived after only chemotherapy or radiotherapy. There were 11 cases of all patients in continue complete remission (CCS), the average CCS time was 47.3 months. Conclusion SBP is a type low-grade malignant tumor. Chemotherapy and radiotherapy is the main therapy. The patients can gain satisfactory prognosis with chemoradiotherapy, part of them can progress to MM.
