CAJ | 학술논문

目的：筛选并证实在高原低氧环境中能改善人体工作能力的有效药物。方法：随机选择海拔3700m某施工部队健康青年24名，分组各12人，自愿分别服用报道对人体有改善代谢作用的红景天胶囊和乙酰唑胺片剂，服药前后均进行24h睡眠剥夺及同等负荷的自行车功量运动，采用DDX-200型电脑多功能心理生理测试仪进行视觉注意分配，左右脚交叉动作频率的对比测验。结果：服用红景天和乙酰唑胺后视觉注意分配和左右脚交叉动作频率操作的总次数、正确次数显著增多(p＜0.01或p＜0.05)。错误次数显著减少(p＜0.01)。结论：口服红景天或乙酰唑胺均能显著改善和提高高原移居者脑—体工作能力，红景天作用稍优于乙酰唑胺。
목적：사선병증실재고원저양배경중능개선인체공작능력적유효약물。방법：수궤선택해발3700m모시공부대건강청년24명，분조각12인，자원분별복용보도대인체유개선대사작용적홍경천효낭화을선서알편제，복약전후균진행24h수면박탈급동등부하적자행차공량운동，채용DDX-200형전뇌다공능심리생리측시의진행시각주의분배，좌우각교차동작빈솔적대비측험。결과：복용홍경천화을선서알후시각주의분배화좌우각교차동작빈솔조작적총차수、정학차수현저증다(p＜0.01혹p＜0.05)。착오차수현저감소(p＜0.01)。결론：구복홍경천혹을선서알균능현저개선화제고고원이거자뇌—체공작능력，홍경천작용초우우을선서알。
Objective: To study the effects of rhodiola and acetazolamide on hypoxia with high altitude. Method: 24 healthy soldiers living and working at a plateau 3700 m above sea level were divided into two groups: rhodiola group (12 cases) and acetazolamide group (12 cases). The two drugs were administrated orally. DDX-200 multifunction psychological machine were used to do psychological tests (vision division test and left/right feet cross exercise) under the stress of sleep deprivation (24 hours) and physical exercise, before and after drug administration respectively. Result: After drug administration, the total count, rate of correct performance in vision division and left/right feet cross tests were increased significantly (p＜0.01 and p＜0.05 respectively), while the rate of false performance in the above two tests decreased markedly (p＜0.01). Conclusion: Rhodiola and Acetazolamide can improve the achievements in psychological tests under stress in high altitude area.