中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
10期
1299-1301
,共3页
脂肪肝%柴胡疏肝散%多烯磷脂酰胆碱
脂肪肝%柴鬍疏肝散%多烯燐脂酰膽堿
지방간%시호소간산%다희린지선담감
Fatty liver%Caihu shugan san%Polyene phosphatidylcholine
目的 探讨柴胡疏肝散联合多烯磷脂酰胆碱治疗非酒精性脂肪肝的临床效果.方法 90例患者随机分为三组,分别为多烯磷脂酰胆碱组(A组)、柴胡疏肝散组(B组)和柴胡疏肝散联合多烯磷脂酰胆碱组(C组),每组30例.比较各组患者治疗前后临床症候评分、生化检查指标[肝功能指标:丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、谷氨酰转移酶(GGT)、总胆红素(TBIL).血脂检查指标:总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HLD-C)、低密度脂蛋白胆固醇(LDL-C)]及B超检查下病情分度.结果 三组组内治疗前后临床症候评分、ALT、AST、GGT、TBIL、TC、TG、LDL-C差异均有统计学意义(均P＜0.05).治疗后,C组临床症候评分、ALT、AST、TBIL、LDL-C的改善情况优于A、B组(P＜0.05);对TC、TG 的作用,B、C组效果相当,均优于A组(均P＜0.05).结论 柴胡疏肝散联合多烯磷脂酰胆碱治疗非酒精性脂肪肝的效果优于两药单独应用,有较好的临床应用前景.
目的 探討柴鬍疏肝散聯閤多烯燐脂酰膽堿治療非酒精性脂肪肝的臨床效果.方法 90例患者隨機分為三組,分彆為多烯燐脂酰膽堿組(A組)、柴鬍疏肝散組(B組)和柴鬍疏肝散聯閤多烯燐脂酰膽堿組(C組),每組30例.比較各組患者治療前後臨床癥候評分、生化檢查指標[肝功能指標:丙氨痠氨基轉移酶(ALT)、天鼕氨痠氨基轉移酶(AST)、穀氨酰轉移酶(GGT)、總膽紅素(TBIL).血脂檢查指標:總膽固醇(TC)、甘油三酯(TG)、高密度脂蛋白膽固醇(HLD-C)、低密度脂蛋白膽固醇(LDL-C)]及B超檢查下病情分度.結果 三組組內治療前後臨床癥候評分、ALT、AST、GGT、TBIL、TC、TG、LDL-C差異均有統計學意義(均P＜0.05).治療後,C組臨床癥候評分、ALT、AST、TBIL、LDL-C的改善情況優于A、B組(P＜0.05);對TC、TG 的作用,B、C組效果相噹,均優于A組(均P＜0.05).結論 柴鬍疏肝散聯閤多烯燐脂酰膽堿治療非酒精性脂肪肝的效果優于兩藥單獨應用,有較好的臨床應用前景.
목적 탐토시호소간산연합다희린지선담감치료비주정성지방간적림상효과.방법 90례환자수궤분위삼조,분별위다희린지선담감조(A조)、시호소간산조(B조)화시호소간산연합다희린지선담감조(C조),매조30례.비교각조환자치료전후림상증후평분、생화검사지표[간공능지표:병안산안기전이매(ALT)、천동안산안기전이매(AST)、곡안선전이매(GGT)、총담홍소(TBIL).혈지검사지표:총담고순(TC)、감유삼지(TG)、고밀도지단백담고순(HLD-C)、저밀도지단백담고순(LDL-C)]급B초검사하병정분도.결과 삼조조내치료전후림상증후평분、ALT、AST、GGT、TBIL、TC、TG、LDL-C차이균유통계학의의(균P＜0.05).치료후,C조림상증후평분、ALT、AST、TBIL、LDL-C적개선정황우우A、B조(P＜0.05);대TC、TG 적작용,B、C조효과상당,균우우A조(균P＜0.05).결론 시호소간산연합다희린지선담감치료비주정성지방간적효과우우량약단독응용,유교호적림상응용전경.
Objective To evaluate the efficacy of chaihu shugan san plus polyene phosphatidylcholine for non-alcoholic fatty liver disease(NAFLD).Methods Ninety patients with NAFLD were randomly divided into 3groups(each n=30):polyene phosphatidylcholine group(Group A),chaihu shugan san group(Group B),and chaihu shugan san plus polyene phosphatidylcholine group(Group C).The clinical symptom scores,biochemistry index (ALT,AST,GGT,TBIL,TC,TG,HLD-C,LDL-C),and B ultrasound examination were measured.Results There were significant differences in clinical symptom scores,ALT,AST,GGT,TBIL,TC,TG,and LDL-C between before and after treatment in the three groups(P＜0.05).After treatment,the clinical symptom scores,ALT,AST,TBIL,and LDL-C in Group C were significantly lower than those in Group A and Group B(P＜0.05).There were similar effects on TC and TG between Group B and Groop C,which were better than those in Group A(P＜0.05).Conclusion The efficacy of combined treatment of chaihu shugan san and polyene phosphatidylcholine was better than that of merely chaihu shugan san or tiopronin.
