CAJ | 학술논문

目的:探讨异丙酚联合舒芬太尼用于儿童纤维胃镜检查的可行性和安全性.方法:接受胃镜检查者120例,随机分为芬太尼组(F组)和舒芬太尼组(S组),每组60例,分别静脉注射咪达唑仑0.05 mg/kg、阿托品0.01 mg/kg,F组给以芬太尼1μg/kg,S组给以舒芬太尼0.1μg/kg,两组给予异丙酚2 mg/kg,待患儿睫毛反射消失后插入胃镜,记录麻醉诱导前、置镜时、手术结束时的心率(HR)、平均动脉压(MAP)、脉搏氧饱和度(S_pO_2),同时记录注射部位是否疼痛、完全清醒时间、术中不适、术后舌后坠、恶心呕吐、眩晕以及两组异丙酚用量等.结果:F组在置镜时HR、MAP高于麻醉诱导前(P＜0.05),术中最低S_pO_2低于麻醉诱导前(P＜0.05);S组HR、MAP在各时点差异无统计学意义(P＞0.05),术中最低S_pO_2低于麻醉诱导前(P＜0.05).组间比较,麻醉诱导前两组HR、MAP、S_pO_2差异无统计学意义,置镜时S组HR、MAP低于F组(P＜0.05),术中最低S_pO_2高于F组(P＜0.05),注射部位疼痛、完全清醒时间、术中不适、眩晕以及异丙酚的总用量均低于F组(P＜0.05).结论:异丙酚联合舒芬太尼麻醉用于儿童纤维胃镜检查,HR、MAP更平稳,呼吸抑制轻,苏醒质量高.
목적:탐토이병분연합서분태니용우인동섬유위경검사적가행성화안전성.방법:접수위경검사자120례,수궤분위분태니조(F조)화서분태니조(S조),매조60례,분별정맥주사미체서륜0.05 mg/kg、아탁품0.01 mg/kg,F조급이분태니1μg/kg,S조급이서분태니0.1μg/kg,량조급여이병분2 mg/kg,대환인첩모반사소실후삽입위경,기록마취유도전、치경시、수술결속시적심솔(HR)、평균동맥압(MAP)、맥박양포화도(S_pO_2),동시기록주사부위시부동통、완전청성시간、술중불괄、술후설후추、악심구토、현훈이급량조이병분용량등.결과:F조재치경시HR、MAP고우마취유도전(P＜0.05),술중최저S_pO_2저우마취유도전(P＜0.05);S조HR、MAP재각시점차이무통계학의의(P＞0.05),술중최저S_pO_2저우마취유도전(P＜0.05).조간비교,마취유도전량조HR、MAP、S_pO_2차이무통계학의의,치경시S조HR、MAP저우F조(P＜0.05),술중최저S_pO_2고우F조(P＜0.05),주사부위동통、완전청성시간、술중불괄、현훈이급이병분적총용량균저우F조(P＜0.05).결론:이병분연합서분태니마취용우인동섬유위경검사,HR、MAP경평은,호흡억제경,소성질량고.
Objective: To investigate the feasibility and clinic effect of anesthesia with propofol-sufentanil in gastrofiberscopy in children. Methods:One hundred and twenty patients scheduled for elective gastrofiberscopy were randomized into two groups:group fentanyl (F) and group sufentanil(S) (n =60). group F were given intravenou midazolam 0.05 mg/kg,atropine 0.01 mg/kg, fentanyl 1 μg/kg, propofol 2 mg/kg, group S were given intravenou midazolam 0.05 mg/kg,atropine 0.01 mg/kg, sufentanil 0.01 μg/kg, propofol 2 mg/kg. The gas-trofiberscope was inserted after lash reflex had been extinct. Total dose of propofol, heart rate(HR),mean arterial pressure (MAP), pulse oxygen saturation ( S_pO_2), time of full recovery ( answering correctly and walking without aid ), discomfort self-feeling were recorded and nausea and vomiting or dinus were noted. Results: At insertion of gastrofiberscope there was significant difference between MAP and HR in group F(P ＜0.05 ), There was no significant difference in MAP and HR in group S(P＞0.05). Compared with group F, there was significant difference in MAP,HR,S_pO_2 at insertion of gastrofiberscope in group S (P＜0.05). Pain, dose of propofol, time of full recovery, discomfort self-feeling in group S were lower than those in group F. Conclusion: More stable HR and MAP lower respiratory depression, better recovery were achieved in children receving gastrofiberscopy with propofol-sufentanyl as anesthesis.