中华皮肤科杂志
中華皮膚科雜誌
중화피부과잡지
Chinese Journal of Dermatology
2012年
2期
114-116
,共3页
范文葛%魏梅%陶晓瑜%宋琳毅%张青松%王玲
範文葛%魏梅%陶曉瑜%宋琳毅%張青鬆%王玲
범문갈%위매%도효유%송림의%장청송%왕령
毛囊炎%秃发%少见病
毛囊炎%禿髮%少見病
모낭염%독발%소견병
Folliculitis%Alopecia%Rare diseases
患者男,24岁.因头皮脓疱、萎缩性瘢痕伴脱发6年.皮肤科检查:头皮弥漫性秃发伴萎缩性瘢痕.头顶仅残留少数头发,发根处有角化性丘疹、脓疱或黑色痂,前额、颞、枕部近发际处尚有部分头发,枕部头发成小簇,发根处见角化性丘疹.眉弓有红斑、鳞屑及毛囊角化性丘疹,眉毛稀疏、脱落.腋毛也稀疏.两颊、腋、胸、腹、后背、四肢均有明显毛囊角化性丘疹.口腔科检查:上下前牙排列间隙过大,上前牙前倾,(+1)先天性缺失,前牙深覆(牙合),深覆盖.沟纹舌,丝状乳头消失.皮损组织病理:表皮棘层增厚,毛囊周围可见大量浆细胞、中性粒细胞及多核巨细胞浸润.结合临床及组织病理表现,符合棘状秃发性毛囊炎的诊断.
患者男,24歲.因頭皮膿皰、萎縮性瘢痕伴脫髮6年.皮膚科檢查:頭皮瀰漫性禿髮伴萎縮性瘢痕.頭頂僅殘留少數頭髮,髮根處有角化性丘疹、膿皰或黑色痂,前額、顳、枕部近髮際處尚有部分頭髮,枕部頭髮成小簇,髮根處見角化性丘疹.眉弓有紅斑、鱗屑及毛囊角化性丘疹,眉毛稀疏、脫落.腋毛也稀疏.兩頰、腋、胸、腹、後揹、四肢均有明顯毛囊角化性丘疹.口腔科檢查:上下前牙排列間隙過大,上前牙前傾,(+1)先天性缺失,前牙深覆(牙閤),深覆蓋.溝紋舌,絲狀乳頭消失.皮損組織病理:錶皮棘層增厚,毛囊週圍可見大量漿細胞、中性粒細胞及多覈巨細胞浸潤.結閤臨床及組織病理錶現,符閤棘狀禿髮性毛囊炎的診斷.
환자남,24세.인두피농포、위축성반흔반탈발6년.피부과검사:두피미만성독발반위축성반흔.두정부잔류소수두발,발근처유각화성구진、농포혹흑색가,전액、섭、침부근발제처상유부분두발,침부두발성소족,발근처견각화성구진.미궁유홍반、린설급모낭각화성구진,미모희소、탈락.액모야희소.량협、액、흉、복、후배、사지균유명현모낭각화성구진.구강과검사:상하전아배렬간극과대,상전아전경,(+1)선천성결실,전아심복(아합),심복개.구문설,사상유두소실.피손조직병리:표피극층증후,모낭주위가견대량장세포、중성립세포급다핵거세포침윤.결합림상급조직병리표현,부합극상독발성모낭염적진단.
A 24-year-old man presented with a 6-year history of pustules,atrophic scars,and alopecia of the scalp.Dermatological examinations showed generalized alopecia and atrophic scarring of the scalp.A few hairs remained at the vertex region with keratotic papules,pustules,or black sears around the hair follicles.There were also residual hairs at the forehead,temples,and occipital region near the hairline.Clusters of hairs were noted in the occipital region,and keratotic papules were observed around the hair follicles.Erythema,scales,and follicular keratotic papules were found in the superciliary arch.The eyebrows and axillary hairs partially shed and were sparse.Follicular keratotic papules were also found on both cheeks,axillae,chest,abdomen,back and limbs.Stomatological examinations revealed a large space between the upper and lower anterior teeth,anteverted upper anterior teeth,congenital absence of (+1) tooth,deep overbite and deep overjet of anterior teeth.He had a fissured tongue which lacked filiform papillae.Pathological examinations of the skin lesions showed a thickened spinous layer and massive infiltrations of plasmacytes, neutrophils, and multinucleated giant cells around hair follicles.A diagnosis of folliculitis spinulosa decalvans was made based on the clinical manifestations and histopathological findings.