CAJ | 학술논문

目的探讨丘脑海绵状血管畸形的手术治疗及预后.方法对27例手术治疗的丘脑海绵状血管畸形的临床资料进行回顾性分析并随访评价.结果 27例患者共出血48次,术前KPS评分为(64.1±9.7)分.经三角区入路18例,胼胝体入路4例,其他入路5例.病灶全切26例,近全切1例.平均随访(48.7±43.2)个月,肢体力弱(53％)、肢体麻木(61％)、行走困难(25％)和视力(67％)等症状较术前改善,而言语表达无明显改善.随访KPS评分为(81.1±15.8)分,其中22例改善,5例稳定.术前KPS评分＞70分(P=0.04)和女性(P=0.028)与预后显著相关.结论手术治疗丘脑海绵状血管畸形可取得良好预后.
목적 탐토구뇌해면상혈관기형적수술치료급예후.방법 대27례수술치료적구뇌해면상혈관기형적림상자료진행회고성분석병수방평개.결과 27례환자공출혈48차,술전KPS평분위(64.1±9.7)분.경삼각구입로18례,변지체입로4례,기타입로5례.병조전절26례,근전절1례.평균수방(48.7±43.2)개월,지체력약(53％)、지체마목(61％)、행주곤난(25％)화시력(67％)등증상교술전개선,이언어표체무명현개선.수방KPS평분위(81.1±15.8)분,기중22례개선,5례은정.술전KPS평분＞70분(P=0.04)화녀성(P=0.028)여예후현저상관.결론 수술치료구뇌해면상혈관기형가취득량호예후.
Objective The goal of this study was to retrospectively analyze the natural history of thalamic cavernomas and outcome after surgical resection.Method The authors retrospectively analyzed the presentation,surgery and outcomes in 27 consecutive patients who underwent microresection of thalamic cavernous malformation.Results Forty - eight times of hemorrhage occurred to 27 patients with a preoperative Karnofsky Performance Scale (KPS) of 64.1 ± 9.7.Eighteen patients underwent transtrigone lateral ventricle approach,four patients experienced interhemispheric transcallosal approach,and other approaches were applied for the remaining five patients and complete resection was achieved in 96％ of patients.After a mean follow - up duration of (48.7 ± 43.2) months,symptoms of weakness,paresthesia,difficulty in walking and vision improved by 53％,61％,25％ and 67％.However,verbalization did not improved obviously.The recent KPS was 81.1 ± 15.8,22 patients improved and 5 stabilized.Preoperative status and gender were the positive predictors of outcome.Conclusions Patients with thalamic cavernous malformation could obtain favorite prognosis through microsurgery.