CAJ | 학술논문

目的了解安徽省皖汀地区自然人群乙型肝炎(乙肝)病毒(HBV)感染状况.方法采用分层整群抽样方法对皖汀地区自然人群进行问卷调查并采集血标本,用ELISA方法检测HBV感染标志.结果在2282例血清标本中,乙肝HBsAg、HBsAb、HBeAg、HBeAb及HBcAb流行率分别为9.8%、43.5%、1.0%、7.8%、10.3%;HBV总感染率(HBV流行率)为40.6%(926/2282).HBsAg流行率男性高于女性(X2=3.992,P＜0.05).乙肝疫苗的接种率为24.7%(539/2178),10岁以下年龄组疫苗接种率最高为97.4%(76/78),学生疫苗接种率较高为78.2%(355/454),乙肝疫苗接种率农村低于城市.接种乙肝疫苗后HBsAg及HBV流行率均显著降低(P＜0.01).结论皖江地区HBsAg的标化流行率为9.3%,为全国乙肝高流行区;尤其是农村地区乙肝疫苗接种率偏低.
목적 료해안휘성환정지구자연인군을형간염(을간)병독(HBV)감염상황.방법 채용분층정군추양방법대환정지구자연인군진행문권조사병채집혈표본,용ELISA방법검측HBV감염표지.결과 재2282례혈청표본중,을간HBsAg、HBsAb、HBeAg、HBeAb급HBcAb류행솔분별위9.8%、43.5%、1.0%、7.8%、10.3%;HBV총감염솔(HBV류행솔)위40.6%(926/2282).HBsAg류행솔남성고우녀성(X2=3.992,P＜0.05).을간역묘적접충솔위24.7%(539/2178),10세이하년령조역묘접충솔최고위97.4%(76/78),학생역묘접충솔교고위78.2%(355/454),을간역묘접충솔농촌저우성시.접충을간역묘후HBsAg급HBV류행솔균현저강저(P＜0.01).결론 환강지구HBsAg적표화류행솔위9.3%,위전국을간고류행구;우기시농촌지구을간역묘접충솔편저.
Objective To describe the epidemic status of hepatitis B along the Yangzi River area,ill Anhui province.Methods A croSS-sectional seroepidemiological survey was conducted and the samples were collected by stratified cluster sampling.Serological biomarkers to hepatitis B virus were tested using enzyme-linked immunosorbent assay(ELISA)reagents.Results Among 2282 people.the prevalence rates of HBsAg,HBsAb,HBeAg.HBeAb,HBeAb and hepatitis B virus infection were 9.8%,43.5%.1.0%,7.8%,10.3%and 40.6%respectively.The prevalence rate of HBsAg among males was higllel"than that offemales(P＜0.05).The vaccination rate was 24.7%,higher in urban than in taral areas.The vaccination rate was high in children younger than ten years old and in students.The prevalence rates of HBsAg and HBV among people who had received vaccines were lower than those who had not.Conclusion The standardized prevalence rates of HBsAg(9.3%)Was high in the area along the Yangzi River in Althai province.The vaccinate rate Was low in the country side.Expanded vaccinate which can obviously reduce the prevalence rate of HBsAg should be enhanced.