CAJ | 학술논문

目的探讨胃肠道肿瘤围手术期预防性抗生素的合理应用.方法选择胃肠道肿瘤外科手术患者104例,将患者分为术前一次性使用抗生素或术后8 h或24 h追加1次量(1组)与传统术后连续使用(2组),观察其术后发生感染的发生率.结果两组术后切口/或手术部位以及肺部和秘尿系统等感染率相比较,无显著性差异(P<0.05).结论对胃肠道肿瘤围手术期术前一次性(或术后8h或24 h追加1次量)使用头孢曲松或头孢拉啶或加甲硝唑可以达到预防性作用;而术后连续使用抗生索除造成浪费外还将引起细菌的耐药性.
목적 탐토위장도종류위수술기예방성항생소적합리응용.방법 선택위장도종류외과수술환자104례,장환자분위술전일차성사용항생소혹술후8 h혹24 h추가1차량(1조)여전통술후련속사용(2조),관찰기술후발생감염적발생솔.결과 량조술후절구/혹수술부위이급폐부화비뇨계통등감염솔상비교,무현저성차이(P<0.05).결론 대위장도종류위수술기술전일차성(혹술후8h혹24 h추가1차량)사용두포곡송혹두포랍정혹가갑초서가이체도예방성작용;이술후련속사용항생색제조성낭비외환장인기세균적내약성.
Objective To analyze the use of antibiotics in perioperative period of gastrointestinal tumor. Methods 104 cases were divided into two groups. Group 1 was treated with antibiotics only once before surgical or at 8 or 24 hours after surgical. Group 2 was treated with antibiotics continuoualy as traditional after sur-gical. And the infection rate was analyzed. Results The infection rate in incision, lung, urological system and so on had no differences between two groups. Conclusions During perioperative period of gastrointestinal tumor, u-sing antibiotics before surgical only once can get prophylaxis purpose. And the traditional way is not only waste but also can lead to antibiotics resistance.