CAJ | 학술논문

研究评价6周游泳运动对载脂蛋白E（apoE-／-）敲除的6周龄大鼠脂质代谢和动脉粥样硬化的影响。大鼠分为对照组（n=7）和运动组（n=7）。运动组大鼠进行6周递增负荷游泳运动，每周均按照第一天10分钟，每周5天（每天增加10分钟，直到连续运动1小时）。评价运动前和运动后血浆总胆固醇。处死大鼠后评价胸、腹主动脉粥样硬化的面积。体重、脂代谢两组结果相似。运动组的相关统计指数降低，表明apoE-/-大鼠游泳运动后动脉粥样硬化病变减少。但这种改变与脂肪代谢无关。
연구평개6주유영운동대재지단백E（apoE-／-）고제적6주령대서지질대사화동맥죽양경화적영향。대서분위대조조（n=7）화운동조（n=7）。운동조대서진행6주체증부하유영운동，매주균안조제일천10분종，매주5천（매천증가10분종，직도련속운동1소시）。평개운동전화운동후혈장총담고순。처사대서후평개흉、복주동맥죽양경화적면적。체중、지대사량조결과상사。운동조적상관통계지수강저，표명apoE-/-대서유영운동후동맥죽양경화병변감소。단저충개변여지방대사무관。
This study evaluated the effects of 6 weeks of swimming on lipid metabolism, and atheroselerosis in 6 - week - old female apolipoprotein E - deficient mice （ apoE -/- ） . The mice were divided into a control group （ n = 7 ） and a exercise group （ n = 7 ） . Mice in the exercise group were required to swim 10 min· d-1, 5d · wk-1 for 6 weeks （which was increased by 10 rain · d-1 until the mice swam continuously for I hr） . Plasma total cholesterol was evaluated before and after the experiment. Atherosclerotic area of tho- racic and abdominal aorta was evaluated after euthanasia. Body weight, lipid metabolism was similar in both groups. Relative index was statistically decreased in the experimental group, thus suggesting that the apoE -/- mice that underwent the swimming exercise exhibi- ted decreased atherosclerotic lesions in the aorta. However, the decrease was not due to changes in lipid metabolism.