CAJ | 학술논문

采用半定量RT-PCR的方法检测死亡相关蛋白激酶(death associated protein kinase, DAPK)基因在口腔鳞状细胞癌(Oral squamous cell carcinoma, OSCC)中的表达,探讨DAPK基因的表达与OSCC的关系,结果显示DAPK基因的表达在OSCC组织中显著降低,该基因可能与OSCC的发生、发展有关,可作为OSCC诊断的检测指标.
채용반정량RT-PCR적방법검측사망상관단백격매(death associated protein kinase, DAPK)기인재구강린상세포암(Oral squamous cell carcinoma, OSCC)중적표체,탐토DAPK기인적표체여OSCC적관계,결과현시DAPK기인적표체재OSCC조직중현저강저,해기인가능여OSCC적발생、발전유관,가작위OSCC진단적검측지표.
To investigate the relationship between the expression of death associated protein kinase (DAPK) gene and oral squamous cell carcinoma (OSCC). The expression of DAPK gene in OSCC was detected by semi-quantitive RT-PCR. The results showed that the expression of DAPK gene was down regulated significantly, which may relate to the tumorigenesis and development of OSCC. The detection of DAPK gene may act as an index in OSCC dignosis.