CAJ | 학술논문

目的:探讨影响胰腺癌的预后因素.方法:对113例病例资料完整的胰腺癌病例进行回顾性统计,应用COX比例风险模型对9项指标进行了多因素分析,并用Kap-lan-Meier法计算其生存率.结果:本组生存期0.1～82.0个月,中位生存期3.0个月.6、12、18、36月的生存率分别为35.6%、20.3%、15.9%、6.2%.多变量分析显示,影响胰腺癌预后最明显的因素是黄疸、转移、治疗方式以及是否行综合治疗.结论:胰腺癌预后由多种因素决定,伴有黄疸、转移的胰腺癌病人预后差,行根治性切除术、综合治疗可改善预后.
목적:탐토영향이선암적예후인소.방법:대113례병례자료완정적이선암병례진행회고성통계,응용COX비례풍험모형대9항지표진행료다인소분석,병용Kap-lan-Meier법계산기생존솔.결과:본조생존기0.1～82.0개월,중위생존기3.0개월.6、12、18、36월적생존솔분별위35.6%、20.3%、15.9%、6.2%.다변량분석현시,영향이선암예후최명현적인소시황달、전이、치료방식이급시부행종합치료.결론:이선암예후유다충인소결정,반유황달、전이적이선암병인예후차,행근치성절제술、종합치료가개선예후.
Objective: To evaluate the major prognostic factors in patients with pancreatic carcinoma.Methods: 113 cases of a particular disease were retrospectively analysed and 9 factors for prognosis were studied by multivaritate analysis with Cox proportional hazards survival model. Survival rate was calculated by Kaplan-Meier estimation. Results:In this group,survival time was 0.1 to 82 months,and the median survival time was 3 months. Overall survival rates at month 6,12,18,36 were 35.6%, 20.3%, 15.9% and 6.2%, respectively. Multivariate analyses revealed significant prognostic factors as follows: jaundice, metastasis, therapy method and synthetic therapy. Conclusion: The prognosis of pancreatic carcinoma is determined by various factors. Jaundice and metastasis are independent predictors of poor survival. Radical operation and synthetic therapy will improve the prognosis.