CAJ | 학술논문

胞外信号可经过相应的转导途径传至胞内，通过激活靶分子而产生细胞效应.细胞凋亡是受控于生物体精确调节的细胞主动消亡过程，具有独特而复杂的信号系统.特异性的胞膜蛋白及膜脂等皆可介导凋亡相关分子的级联激活，并通过活化凋亡关键调节分子Caspases蛋白酶家族，bcl-2基因家族及线粒体等而影响凋亡的进程.
포외신호가경과상응적전도도경전지포내，통과격활파분자이산생세포효응.세포조망시수공우생물체 정학조절적세포주동소망과정，구유독특이복잡적신호계통.특이성적포막단백급막지등개가개도조망상관분 자적급련격활，병통과활화조망관건조절분자Caspases단백매가족，bcl-2기인가족급선립체등이영향조망적 진정.
A variety of extra-cellular signals could activate the target molecules and induce the associated biological effects depended on different signal pathways. Apoptosis, or programmed cell death, is a conservation process essential for normal development and homeostasis of biologist. It's known that a number of factors and pathways can lead to apoptosis. Specific phosphorlipids and proteins of biomembrane could activate the signal cascades of apoptosis. The interaction of caspases, bcl-2 family and mitochondria play an essential role in regulation of apoptosis.