CAJ | 학술논문

目的研究高血压、视网膜动脉硬化与年龄相关性黄斑变性发病的相关性.方法前瞻性系列病例研究.收集296名体检患者的临床资料,包括全身和眼部的诊治详情.按性别不同,分别统计高血压、视网膜动脉硬化、年龄相关性黄斑变性的发病率,分析高血压、视网膜动脉硬化与年龄相关性黄斑变性之间的相关性.结果高血压患者中并发年龄相关性黄斑变性的发病率明显高于血压正常人年龄相关性黄斑变性的发病率(x2=15.72,P＜ 0.01)；视网膜动脉硬化患者中年龄相关性黄斑变性的发病率也显著高于无视网膜动脉硬化者的年龄相关性黄斑变性的发病率(x2=23.74,P＜0.01),两组对照相比差异有统计学意义.高血压的程度与年龄相关性黄斑变性的发病率呈正相关关系(F=0.743,P＜0.05).结论高血压、视网膜动脉硬化与年龄相关性黄斑变性三者之间关联紧密,高血压、视网膜动脉硬化可能是年龄相关性黄斑变性发病的危险因素之一.
목적 연구고혈압、시망막동맥경화여년령상관성황반변성발병적상관성.방법 전첨성계렬병례연구.수집296명체검환자적림상자료,포괄전신화안부적진치상정.안성별불동,분별통계고혈압、시망막동맥경화、년령상관성황반변성적발병솔,분석고혈압、시망막동맥경화여년령상관성황반변성지간적상관성.결과 고혈압환자중병발년령상관성황반변성적발병솔명현고우혈압정상인년령상관성황반변성적발병솔(x2=15.72,P＜ 0.01)；시망막동맥경화환자중년령상관성황반변성적발병솔야현저고우무시망막동맥경화자적년령상관성황반변성적발병솔(x2=23.74,P＜0.01),량조대조상비차이유통계학의의.고혈압적정도여년령상관성황반변성적발병솔정정상관관계(F=0.743,P＜0.05).결론 고혈압、시망막동맥경화여년령상관성황반변성삼자지간관련긴밀,고혈압、시망막동맥경화가능시년령상관성황반변성발병적위험인소지일.
Objective To explore the relationship of retinal atherosclerosis and hypertension with the genesis of age-related macular degeneration ( AMD ).Methods This study was a retrospective review.The clinical data on 296 patients who had physical examinations including general and eye examinations were colleced.The incidence rates of retinal atherosclerosis,hypertension,and AMD were counted according to different sex.The relationship of hypertension and retinal atherosclerosis with AMD was analyzed.Results The incidence rate of AMD in hypertensive patients was markedly higher than that in normotensive people ( x2=1 5.72,P ＜ 0.01 ); and the incidence rate of AMD in patients with retinal atherosclerosis was also markedly higher than that in those without reinal atherosclerosis ( x2 =23.74,P＜0.01 ).Conclusions Retinal atherosclerosis and hypertension are closed related with age-related macular degeneration.The former two medical conditions are likely one of the risk factors for the latter disorder.