中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2009年
23期
2165-2166
,共2页
重症急性胰腺炎%影响因素%预后
重癥急性胰腺炎%影響因素%預後
중증급성이선염%영향인소%예후
Severe acute pancreatitis%Influencing factors%Prognosis
目的 探讨重症急性胰腺炎(severe acute pancreatitis,SAP)继发胰腺感染的影响因素,以早期采取有针对性的干预措施,降低病死率.方法 选择我院2004-2008年收治的36例重症急性胰腺炎患者,按有无继发感染分为两组,感染组与非感染组,先以单因素分析筛选有统计学意义的影响因素,再通过逐步Logistic回归分析筛选与继发感染有关的影响因素.结果 两组患者中心静脉导管留置时间、禁食时间、有无低氧血症、胃肠道障碍时间、血清清蛋白水平方面差异有统计学意义(P<0.05).重症胰腺炎患者继发胰腺感染相关因素的Logistic回归分析显示:中心静脉导管留置时间、禁食时间、有无低氧血症、胃肠道障碍时间与继发胰腺感染明显相关(OR值分别为1.17、1.41、1.37和1.58,P<0.05).结论 中心静脉导管留置时间、禁食时间、有无低氧血症、胃肠道障碍时间与继发胰腺感染明显相关.应引起注意,入院开始有针对性地进行干预,可减少病死率,改善预后.
目的 探討重癥急性胰腺炎(severe acute pancreatitis,SAP)繼髮胰腺感染的影響因素,以早期採取有針對性的榦預措施,降低病死率.方法 選擇我院2004-2008年收治的36例重癥急性胰腺炎患者,按有無繼髮感染分為兩組,感染組與非感染組,先以單因素分析篩選有統計學意義的影響因素,再通過逐步Logistic迴歸分析篩選與繼髮感染有關的影響因素.結果 兩組患者中心靜脈導管留置時間、禁食時間、有無低氧血癥、胃腸道障礙時間、血清清蛋白水平方麵差異有統計學意義(P<0.05).重癥胰腺炎患者繼髮胰腺感染相關因素的Logistic迴歸分析顯示:中心靜脈導管留置時間、禁食時間、有無低氧血癥、胃腸道障礙時間與繼髮胰腺感染明顯相關(OR值分彆為1.17、1.41、1.37和1.58,P<0.05).結論 中心靜脈導管留置時間、禁食時間、有無低氧血癥、胃腸道障礙時間與繼髮胰腺感染明顯相關.應引起註意,入院開始有針對性地進行榦預,可減少病死率,改善預後.
목적 탐토중증급성이선염(severe acute pancreatitis,SAP)계발이선감염적영향인소,이조기채취유침대성적간예조시,강저병사솔.방법 선택아원2004-2008년수치적36례중증급성이선염환자,안유무계발감염분위량조,감염조여비감염조,선이단인소분석사선유통계학의의적영향인소,재통과축보Logistic회귀분석사선여계발감염유관적영향인소.결과 량조환자중심정맥도관류치시간、금식시간、유무저양혈증、위장도장애시간、혈청청단백수평방면차이유통계학의의(P<0.05).중증이선염환자계발이선감염상관인소적Logistic회귀분석현시:중심정맥도관류치시간、금식시간、유무저양혈증、위장도장애시간여계발이선감염명현상관(OR치분별위1.17、1.41、1.37화1.58,P<0.05).결론 중심정맥도관류치시간、금식시간、유무저양혈증、위장도장애시간여계발이선감염명현상관.응인기주의,입원개시유침대성지진행간예,가감소병사솔,개선예후.
Objective To study the risk factors of secondary pancreatic infection (SPI) in patients with severe acute pancreatitis (SAP) in order to take early intervention to reduce mortality. Methods Totally 36 diagnosed SAP patients from January 2004 to December 2008 were divided as SPI group and non-SPI group according to the secondary infection. Single factor analysis was taken to screen the statistically significant risk factors, and then stepwise Logistic regression analysis was used to determine the risk factors to secondary infection. Results There were significant differences between SPI group and non-SPI group in time of central veinous catheterization, fasting time, hypoxemia, time of gastrointestinal tract disorder, and level of serum albumin (P<0.05). Stepwise logistic regression analysis showed that the time of central veinous catheterization, fasting time, hypoxemia, and time of gastrointestinal tract disorder were remarkably associated with secondary pancreatic infection (OR=1.17, 1.41, 1.37 and 1.58 respectively, P<0.05). Conclusion The time of central veinous catheterization, fasting time, hypoxemia, and time of gastrointestinal tract disorder were remarkably associated with secondary pancreatic infection. This should be pay attention to and given target intervention since beginning of hospitalization so as to reduce mortality and improve prognosis.