中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
4期
517-519
,共3页
脑梗死%低密度脂蛋白%血糖%C反应蛋白%白细胞介素6%老年人
腦梗死%低密度脂蛋白%血糖%C反應蛋白%白細胞介素6%老年人
뇌경사%저밀도지단백%혈당%C반응단백%백세포개소6%노년인
Cerebral infarction%Low-density lipoprotein%Blood Sugar%C-reactive protein%Interleukin 6%Aged
目的 探讨老年人急性脑梗死患者血浆氧化型低密度脂蛋白(OX-LDL)、血糖、C-反应蛋白(CRP)和白细胞介素6(IL-6)水平变化及与不同类型急性脑梗死的关系.方法 100例急性脑梗死患者(A组)及30例同期住院的非脑梗死健康患者(B组)行血浆OX-LDL、血糖、CRP、IL-6和颈动脉超声检查.并按低分子肝素试验TOAST病因分型标准分型,对不同类型脑梗死相关危险因素进行分析.结果 A组OXLDL、血糖、CRP和IL-6分别为(627.2±174.7) μg/L、(8.8±1.7) mmol/L、(107.5±19.4) mg/L、(79.5±12.1)ng/L,均高于B组的(506.1±152.4) μg/L、(6.9±1.5) mmol/L、(87.2±13.6)mg/L、(58.5±10.3) ng/L(t=2.74,3.18,2.61,2.91,均P＜0.05).结论 老年人急性脑梗死与血浆OX-LDL、血糖、CRP和IL-6含量升高有关,且血浆OX-LDL增高易发大动脉粥样硬化型脑梗死,血糖增高发生小动脉闭塞型脑梗死的可能性大.
目的 探討老年人急性腦梗死患者血漿氧化型低密度脂蛋白(OX-LDL)、血糖、C-反應蛋白(CRP)和白細胞介素6(IL-6)水平變化及與不同類型急性腦梗死的關繫.方法 100例急性腦梗死患者(A組)及30例同期住院的非腦梗死健康患者(B組)行血漿OX-LDL、血糖、CRP、IL-6和頸動脈超聲檢查.併按低分子肝素試驗TOAST病因分型標準分型,對不同類型腦梗死相關危險因素進行分析.結果 A組OXLDL、血糖、CRP和IL-6分彆為(627.2±174.7) μg/L、(8.8±1.7) mmol/L、(107.5±19.4) mg/L、(79.5±12.1)ng/L,均高于B組的(506.1±152.4) μg/L、(6.9±1.5) mmol/L、(87.2±13.6)mg/L、(58.5±10.3) ng/L(t=2.74,3.18,2.61,2.91,均P＜0.05).結論 老年人急性腦梗死與血漿OX-LDL、血糖、CRP和IL-6含量升高有關,且血漿OX-LDL增高易髮大動脈粥樣硬化型腦梗死,血糖增高髮生小動脈閉塞型腦梗死的可能性大.
목적 탐토노년인급성뇌경사환자혈장양화형저밀도지단백(OX-LDL)、혈당、C-반응단백(CRP)화백세포개소6(IL-6)수평변화급여불동류형급성뇌경사적관계.방법 100례급성뇌경사환자(A조)급30례동기주원적비뇌경사건강환자(B조)행혈장OX-LDL、혈당、CRP、IL-6화경동맥초성검사.병안저분자간소시험TOAST병인분형표준분형,대불동류형뇌경사상관위험인소진행분석.결과 A조OXLDL、혈당、CRP화IL-6분별위(627.2±174.7) μg/L、(8.8±1.7) mmol/L、(107.5±19.4) mg/L、(79.5±12.1)ng/L,균고우B조적(506.1±152.4) μg/L、(6.9±1.5) mmol/L、(87.2±13.6)mg/L、(58.5±10.3) ng/L(t=2.74,3.18,2.61,2.91,균P＜0.05).결론 노년인급성뇌경사여혈장OX-LDL、혈당、CRP화IL-6함량승고유관,차혈장OX-LDL증고역발대동맥죽양경화형뇌경사,혈당증고발생소동맥폐새형뇌경사적가능성대.
Objective To investigate the relationship between different types of acute ischemic stroke in elderly patients and serum oxidized low-density lipoprotein (OX-LDL),blood sugar,C-reactive protein(CRP) and interleukin 6 (IL-6) levels.Methods 100 patients with acute cerebral infarction (group A) and 30 heathy patients (group B)were investigated.The levels of serum OX-LDL,blood sugar,CRP and IL-6 were detected by automatic biochemical analysis.Results The levels of OX-LDL(627.2 ± 174.7 ) μg/L,blood sugar ( 8.8 ± 1.7 ) mmol/L,CRP ( 107.5 ±19.4)mg/L and IL-6(79.5 ± 12.1 )ng/L in patients of group A were significantly higher than group B[ OX-LDL(506.1 ± 152.4) μg/L,blood sugar(6.9 ± 1.5) mmol/L,CRP(87.2 ± 13.6) mg/L and IL-6(58.5 ± 10.3) ng/L](t=2.74,3.18,2.61,2.91,allP＜0.05).Conclusion Elderly patients with acute cerebral infarction were closely related to the elevated levels of plasma OX-LDL,blood sugar,CRP and IL-6.Increased plasma OX-LDL was a risk factor for the main artery atherosclerosis type,and hyperglycemia was primary factor for the small artery atherosclerosis type of acute cerebral infarction.
