CAJ | 학술논문

目的探讨血 β-HCG变化与异位妊娠保守治疗的关系.方法　选择确诊的异位妊娠患者95例行甲氨蝶呤(MTX)单次剂量50 mg/m2/周,治疗l～2周,保守治疗成功(B组)87例,失败(A组)8例.治疗同时测定血B-HCG水平.结果B组患者在治疗1～2周后血IS-HCG值下降＜15%的病例数明显少于A组,差异有统计学意义(P＜0.05).结论定期监测血清 β-HCG水平变化有助于判定药物治疗的效果,在用药物1～周后血清β-HCG值下降仍＜5%者,应适时放弃保守治疗尽早选择手术治疗.
목적 탐토혈 β-HCG변화여이위임신보수치료적관계.방법　선택학진적이위임신환자95례행갑안접령(MTX)단차제량50 mg/m2/주,치료l～2주,보수치료성공(B조)87례,실패(A조)8례.치료동시측정혈B-HCG수평.결과B조환자재치료1～2주후혈IS-HCG치하강＜15%적병례수명현소우A조,차이유통계학의의(P＜0.05).결론 정기감측혈청 β-HCG수평변화유조우판정약물치료적효과,재용약물1～주후혈청β-HCG치하강잉＜5%자,응괄시방기보수치료진조선택수술치료.
Objective To explore the relationship between the change of serum β-HCG and the effect of　conservative treatment in tubal ectopic pregnancy.Methods 95 patients with tubal ectopic pregnancy were treated with single dose methotrexate injection.Among them,87 patients were successfully cured,16 patients were treated with the 2nd dose and Chinese herbal medicine orally:8 patients failed.The change of serum β-HCG levels after the first and 2nd course of treatment were measured.Results It showed that after the first or 2nd course of treatment,the cases which serum β-HCG level reducing less than 15%in patients who had successful treatment were signiflcantly lower than that in patients who failed(P＜0.05).Conclusion Detecting the change of serum β-HCG concentration can evaluate the therapeutic effect in tubal ectopic pregnancy with conservative treatment,and according that surgical operation should be chosen if serum β-HCG reduce less than 15%after two courses of treatment.