中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2009年
4期
376-379
,共4页
李海员%王延平%黄绍宽%杨少青%陈盛强%邓永萍%陈智超
李海員%王延平%黃紹寬%楊少青%陳盛彊%鄧永萍%陳智超
리해원%왕연평%황소관%양소청%진성강%산영평%진지초
轻度认知功能障碍%蒙特利尔认知评估量表
輕度認知功能障礙%矇特利爾認知評估量錶
경도인지공능장애%몽특리이인지평고량표
Mild cognitive impairment%Montreal cognitive assessment
目的 探讨蒙特利尔认知评估量表(MoCA)在轻度认知功能障碍(MCI)患者筛查中的应用.方法 应用简易精神状态检查量表(MMSE)、MoCA对32例MCI患者和50例健康对照者进行神经心理评估,比较二者筛查MCI的效果.结果 以26分为分界值,MoCA筛查MCI的敏感性为96.87%、特异性为76%,MMSE筛查MCI的敏感性为56.25%、特异性为96%;MoCA中除抽象思维、地点定向两项外,其余各亚项的评分在MCI组和对照组间差异均有统计学意义(P<0.05):MMSE中仅计算与注意力、延迟回忆两项在MCI组和对照组间差异有统计学意义(P<0.05),其余各项差异均无统计学意义(P>0.05).结论 MoCA为高敏感性的MCI筛查工具,能全面评估MCI患者的认知功能.且可用于筛查MMSE得分正常的MCI患者.
目的 探討矇特利爾認知評估量錶(MoCA)在輕度認知功能障礙(MCI)患者篩查中的應用.方法 應用簡易精神狀態檢查量錶(MMSE)、MoCA對32例MCI患者和50例健康對照者進行神經心理評估,比較二者篩查MCI的效果.結果 以26分為分界值,MoCA篩查MCI的敏感性為96.87%、特異性為76%,MMSE篩查MCI的敏感性為56.25%、特異性為96%;MoCA中除抽象思維、地點定嚮兩項外,其餘各亞項的評分在MCI組和對照組間差異均有統計學意義(P<0.05):MMSE中僅計算與註意力、延遲迴憶兩項在MCI組和對照組間差異有統計學意義(P<0.05),其餘各項差異均無統計學意義(P>0.05).結論 MoCA為高敏感性的MCI篩查工具,能全麵評估MCI患者的認知功能.且可用于篩查MMSE得分正常的MCI患者.
목적 탐토몽특리이인지평고량표(MoCA)재경도인지공능장애(MCI)환자사사중적응용.방법 응용간역정신상태검사량표(MMSE)、MoCA대32례MCI환자화50례건강대조자진행신경심리평고,비교이자사사MCI적효과.결과 이26분위분계치,MoCA사사MCI적민감성위96.87%、특이성위76%,MMSE사사MCI적민감성위56.25%、특이성위96%;MoCA중제추상사유、지점정향량항외,기여각아항적평분재MCI조화대조조간차이균유통계학의의(P<0.05):MMSE중부계산여주의력、연지회억량항재MCI조화대조조간차이유통계학의의(P<0.05),기여각항차이균무통계학의의(P>0.05).결론 MoCA위고민감성적MCI사사공구,능전면평고MCI환자적인지공능.차가용우사사MMSE득분정상적MCI환자.
Objective To assess the value of Montreal Cognitive Assessment(MoCA)in screening mild cognitive impairment(MCI)in elderly patients.Methods Thirty-two elderly patients with MCI and 50 healthy elderly subjects were examined with neuropsychological tests using Mini-mental State Examination(MMSE)and the MoCA. Results With a cut-off score of 26,the MoCA had a sensitivity of 96.87%and specificity of 76%for detecting MCI,and the sensitivity and specificity of MMSE were 56.25%and 96%,respectively.For the MoCA sub-items,the elderly patients with MCI had significantly lower scores than the healthy elderly in all the cognitive function measures (P<0.05)except for abstraction and fixed orientation.In MMSE sub-items,significant differgnces were found between the two groups in only calculation/attention and delayed recall(P<0.05).Conclusions The MoCA is a highiy sensitive scale for screening MCI in elderly patients,which allows comprehensive assessment of the cognitive function of MCI patients and is applicable in detecting MCI in patients with normal MMSE results.