CAJ | 학술논문

目的探讨蒙特利尔认知评估量表(MoCA)在轻度认知功能障碍(MCI)患者筛查中的应用.方法应用简易精神状态检查量表(MMSE)、MoCA对32例MCI患者和50例健康对照者进行神经心理评估,比较二者筛查MCI的效果.结果以26分为分界值,MoCA筛查MCI的敏感性为96.87%、特异性为76%,MMSE筛查MCI的敏感性为56.25%、特异性为96%;MoCA中除抽象思维、地点定向两项外,其余各亚项的评分在MCI组和对照组间差异均有统计学意义(P＜0.05):MMSE中仅计算与注意力、延迟回忆两项在MCI组和对照组间差异有统计学意义(P＜0.05),其余各项差异均无统计学意义(P＞0.05).结论 MoCA为高敏感性的MCI筛查工具,能全面评估MCI患者的认知功能.且可用于筛查MMSE得分正常的MCI患者.
목적 탐토몽특리이인지평고량표(MoCA)재경도인지공능장애(MCI)환자사사중적응용.방법 응용간역정신상태검사량표(MMSE)、MoCA대32례MCI환자화50례건강대조자진행신경심리평고,비교이자사사MCI적효과.결과 이26분위분계치,MoCA사사MCI적민감성위96.87%、특이성위76%,MMSE사사MCI적민감성위56.25%、특이성위96%;MoCA중제추상사유、지점정향량항외,기여각아항적평분재MCI조화대조조간차이균유통계학의의(P＜0.05):MMSE중부계산여주의력、연지회억량항재MCI조화대조조간차이유통계학의의(P＜0.05),기여각항차이균무통계학의의(P＞0.05).결론 MoCA위고민감성적MCI사사공구,능전면평고MCI환자적인지공능.차가용우사사MMSE득분정상적MCI환자.
Objective To assess the value of Montreal Cognitive Assessment(MoCA)in screening mild cognitive impairment(MCI)in elderly patients.Methods Thirty-two elderly patients with MCI and 50 healthy elderly subjects were examined with neuropsychological tests using Mini-mental State Examination(MMSE)and the MoCA. Results With a cut-off score of 26,the MoCA had a sensitivity of 96.87%and specificity of 76%for detecting MCI,and the sensitivity and specificity of MMSE were 56.25%and 96%,respectively.For the MoCA sub-items,the elderly patients with MCI had significantly lower scores than the healthy elderly in all the cognitive function measures (P＜0.05)except for abstraction and fixed orientation.In MMSE sub-items,significant differgnces were found between the two groups in only calculation/attention and delayed recall(P＜0.05).Conclusions The MoCA is a highiy sensitive scale for screening MCI in elderly patients,which allows comprehensive assessment of the cognitive function of MCI patients and is applicable in detecting MCI in patients with normal MMSE results.