CAJ | 학술논문

目的系统评价胰十二指肠术应用胰肠吻合术(PJ)与胰胃吻合术(PG)的临床疗效.方法计算机检索中英文数据库,对纳入的4篇随机对照试验使用RevManS.0.18软件进行系统评价.结果纳入患者553例.Meta分析显示,PG胆瘘发生率低(0.51％,RR =0.17,P＜0.05)、腹腔积液发生率低(8.70％,RR =0.5,P＜0.01)、腹腔内多发并发症发生率低(5.70％,RR =0.26,P＜0.01),差异有统计学意义.PG组发生胃排空障碍发生率低(10.20％,RR=0.61,P＞0.05)、腹腔内并发症发生率低(29.60％,RR =0.76,P ＞0.05),差异无统计学意义,但倾向于PG.两组胰瘘率、病死率差异均无统计学意义(P＞0.05).结论在胰十二指肠切除术中应用PG是安全的,还需更多高质量的临床随机对照试验(RCT)详细论证.
목적 계통평개이십이지장술응용이장문합술(PJ)여이위문합술(PG)적림상료효.방법 계산궤검색중영문수거고,대납입적4편수궤대조시험사용RevManS.0.18연건진행계통평개.결과 납입환자553례.Meta분석현시,PG담루발생솔저(0.51％,RR =0.17,P＜0.05)、복강적액발생솔저(8.70％,RR =0.5,P＜0.01)、복강내다발병발증발생솔저(5.70％,RR =0.26,P＜0.01),차이유통계학의의.PG조발생위배공장애발생솔저(10.20％,RR=0.61,P＞0.05)、복강내병발증발생솔저(29.60％,RR =0.76,P ＞0.05),차이무통계학의의,단경향우PG.량조이루솔、병사솔차이균무통계학의의(P＞0.05).결론 재이십이지장절제술중응용PG시안전적,환수경다고질량적림상수궤대조시험(RCT)상세론증.
Objective To provide an evidence-based perspective to pancreaticojejunostomy (PJ) versus pancreaticogastrostomy (PG) after pancreaticoduodenec-tomy.Methods We searched English and Chinese database.The Review Manager 5.0.18 software was used for meta analyses and four randomized controlled trials were analyzed.Results 553 patients were included.There was significant difference between PJ and PG regarding postoperative biliary fistula (0.51％,RR =0.17,P ＜ 0.05 ),intra-abdominal fluid collection ( 8.70％,RR =0.5,P ＜ 0.01 ),intra-abdominal multiple complications (5.70％,RR =0.26,P ＜0.01 ).There was no significant difference in delayed gastric emptying ( 10.20％,RR =0.61,P ＞ 0.05 ) and intra-abdominal complications (29.60％,RR =0.76,P ＞ 0.05 ).There was no significant difference in pancreatic fistula ( P＞0.05 ) and mortality ( P＞ 0.05 ).Conclusion PG after pancreaticoduodenectomy is safe.