抗感染药学
抗感染藥學
항감염약학
ANTI-INFECTION PHARMACY
2009年
3期
191-193
,共3页
闻平%俞晓丽%虞建人%王文凯
聞平%俞曉麗%虞建人%王文凱
문평%유효려%우건인%왕문개
比阿培南%致病菌%抗菌活性
比阿培南%緻病菌%抗菌活性
비아배남%치병균%항균활성
目的:评价比阿培南对501株-临床分离致病菌的体外抗茵活性.方法:采用刃天青微孔板稀释法测定比阿培南和对照品(美罗培南、亚胺培南、头孢吡肟、头孢他啶、头孢哌酮/舒巴坦、环丙沙星、苯唑西林、万古霉素)对501株临床分离致病菌的体外抗菌活性.结果:比阿培南对大肠埃希菌、克雷伯菌属、产气肠杆菌、阴沟肠杆菌、志贺菌属、沙门菌属、变形杆菌属、沙雷菌属、柠檬酸菌属、不动杆菌属和铜绿假单胞菌的MIC50分别为0.06,0.13,0.25,0.13,0.03,0.03,1.00,0.50,0.13,0.13,0.50 μg/mL;MIC90分别为0.13,0.13,0.50,0.50,0.03,0.06,1.00,0.50,0.25,0.25,4.00 μg/mL.结论:比阿培南对临床分离致病菌的最低抑茵浓度MIC50、MIC90低于对照品.
目的:評價比阿培南對501株-臨床分離緻病菌的體外抗茵活性.方法:採用刃天青微孔闆稀釋法測定比阿培南和對照品(美囉培南、亞胺培南、頭孢吡肟、頭孢他啶、頭孢哌酮/舒巴坦、環丙沙星、苯唑西林、萬古黴素)對501株臨床分離緻病菌的體外抗菌活性.結果:比阿培南對大腸埃希菌、剋雷伯菌屬、產氣腸桿菌、陰溝腸桿菌、誌賀菌屬、沙門菌屬、變形桿菌屬、沙雷菌屬、檸檬痠菌屬、不動桿菌屬和銅綠假單胞菌的MIC50分彆為0.06,0.13,0.25,0.13,0.03,0.03,1.00,0.50,0.13,0.13,0.50 μg/mL;MIC90分彆為0.13,0.13,0.50,0.50,0.03,0.06,1.00,0.50,0.25,0.25,4.00 μg/mL.結論:比阿培南對臨床分離緻病菌的最低抑茵濃度MIC50、MIC90低于對照品.
목적:평개비아배남대501주-림상분리치병균적체외항인활성.방법:채용인천청미공판희석법측정비아배남화대조품(미라배남、아알배남、두포필우、두포타정、두포고동/서파탄、배병사성、분서서림、만고매소)대501주림상분리치병균적체외항균활성.결과:비아배남대대장애희균、극뢰백균속、산기장간균、음구장간균、지하균속、사문균속、변형간균속、사뢰균속、저몽산균속、불동간균속화동록가단포균적MIC50분별위0.06,0.13,0.25,0.13,0.03,0.03,1.00,0.50,0.13,0.13,0.50 μg/mL;MIC90분별위0.13,0.13,0.50,0.50,0.03,0.06,1.00,0.50,0.25,0.25,4.00 μg/mL.결론:비아배남대림상분리치병균적최저억인농도MIC50、MIC90저우대조품.
