CAJ | 학술논문

目的探讨阿维A联合中药泡浴治疗掌跖部慢性角化性湿疹的疗效.方法 68例患者按就诊顺序随机分为2组.治疗组36例口服阿维A 20mg,午餐时顿服,效果不显著时加量至30 mg,皮损消退后改为10 mg维持,联合中药泡浴;对照组32例口服依巴斯汀10 mg,1次/d,联合中药泡浴.2组均外擦曲安缩松尿素软膏,2次/d,疗程均为4周.结果对照组与治疗组各有2例患者退出观察.对照组有效率60.0%(18/30),治疗组为94.1%(32/34),治疗组24例出现口唇干燥,15例出现皮肤脱屑、皮肤干燥,9例出现皮肤瘙痒,ALT升高3例,AST升高2例,总胆固醇升高3例,胃肠道不适5例,对照组2例轻度嗜睡.上述所有症状经对症处理和停药后均恢复正常,未影响治疗.结论阿维A联合中药泡浴治疗掌跖部慢性角化性湿疹疗效较明显.
목적 탐토아유A연합중약포욕치료장척부만성각화성습진적료효.방법 68례환자안취진순서수궤분위2조.치료조36례구복아유A 20mg,오찬시돈복,효과불현저시가량지30 mg,피손소퇴후개위10 mg유지,연합중약포욕;대조조32례구복의파사정10 mg,1차/d,연합중약포욕.2조균외찰곡안축송뇨소연고,2차/d,료정균위4주.결과 대조조여치료조각유2례환자퇴출관찰.대조조유효솔60.0%(18/30),치료조위94.1%(32/34),치료조24례출현구진간조,15례출현피부탈설、피부간조,9례출현피부소양,ALT승고3례,AST승고2례,총담고순승고3례,위장도불괄5례,대조조2례경도기수.상술소유증상경대증처리화정약후균회복정상,미영향치료.결론 아유A연합중약포욕치료장척부만성각화성습진료효교명현.
Objective To investigate the efficacy of acitretin combined with traditional Chinese herb bath for the treatment of palmoplantar chronic keratotic eczema.Methods Totally 68 patients were randomly divided into two groups:treatment group was treated with oral acitretin and traditional Chinese herbs bath and the control group WaS treated with oral ebastine and traditional Chinese herb bath.The two groups were both treated with triameinolone acetonide et urea ointment.Results The efficaey rate in the treatment group Was 94.12%and it was 60%in the control group(P＜0.05).Conclusion Aeitretin combined with traditional Chinese herbs bath is effective for the treatment of palmoplantar chronic keratotic.