CAJ | 학술논문

目的探讨子宫内膜异位症患者治疗前后血清脂联素和高敏C反应蛋白(Hs-CRP)水平的变化意义.方法采用酶联免疫吸附法(ELISA)检测脂联素含量,同时采用免疫比浊法对血清Hs-CRP进行测定;分别测定46例子宫内膜异位症患者血清脂联素和Hs-CRP含量,并与34名正常健康人作比较.结果在治疗前血清Hs-CRP水平非常显著地高于对照组(P＜0.01),而脂联素水平则显著地低于对照组(P＜0.01),经治疗3个月后,则与对照组比较无统计学意义(P＞0.05).EMS患者治疗前血清脂联紊和Hs-CRP含量呈明显的负相关(r=-0.57,P＜0.01).结论子宫内膜异位症的发生与发展与血清脂联素和Hs-CRP水平密切相关.
목적 탐토자궁내막이위증환자치료전후혈청지련소화고민C반응단백(Hs-CRP)수평적변화의의.방법 채용매련면역흡부법(ELISA)검측지련소함량,동시채용면역비탁법대혈청Hs-CRP진행측정;분별측정46례자궁내막이위증환자혈청지련소화Hs-CRP함량,병여34명정상건강인작비교.결과 재치료전혈청Hs-CRP수평비상현저지고우대조조(P＜0.01),이지련소수평칙현저지저우대조조(P＜0.01),경치료3개월후,칙여대조조비교무통계학의의(P＞0.05).EMS환자치료전혈청지련문화Hs-CRP함량정명현적부상관(r=-0.57,P＜0.01).결론 자궁내막이위증적발생여발전여혈청지련소화Hs-CRP수평밀절상관.
Objective To explore the clinical significance of changes of serum adiponectin and Hs-CRP levels after treatment in patients with endometriosis.Methods Concentrations of resistin were determined by enzyme linked immunosorbent assay(ELISA),and Hs-CRP was determined by rate nephelometry immunoassay.Serum adiponectin and Hs-CRP levels were determined in 46 patients with endometriosis both before and after treatment as well as in 34 controls.Results Before treatment,the serum Hs-CRP levels in patients were significantly higher than those in the controls(P＜0.01).while the adiponectin levels were significantly lower(P＜0.01).After 3 months of treatment all the levels were not significantly different from those in controls(P＞0.05).Conclusion Development of endometriosis were closely related to the serum levels of adiponectin and Hs-CRP.