中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2012年
2期
119-121
,共3页
张帅%张虹霞%李晓辉%胥振扬
張帥%張虹霞%李曉輝%胥振颺
장수%장홍하%리효휘%서진양
社区获得性肺炎%C反应蛋白%肺炎严重指数
社區穫得性肺炎%C反應蛋白%肺炎嚴重指數
사구획득성폐염%C반응단백%폐염엄중지수
Community-acquired pneumonia%C-reactive protein%Pneumonia severity index
目的 探讨C反应蛋白(CRP)及肺炎严重指数(PSI)在社区获得性肺炎(CAP)中的变化,以进一步了解CRP在CAP严重度及预后评估中的作用.方法 我院2009年1月至2011年5月住院CAP患者106例,按PSI评分、是否重症CAP、是否≥65岁患者分别分组,测定血清CRP.结果 CRP与PSI评分呈显著正相关(r=0.453 P=0.000); CAP老年组CRP与PSI评分无相关性,非老年组CRP[(81.70 ±75.63)mg/L]与PSI评分[(78.30±42.63)分]呈显著正相关(r=0.489,P＜0.001)；CAP重症组PSI评分[(89.24±36.44)分]及CRP[(106.93±74.76)mg/L]与非重症组PSI评分[(53.59±35.41)分]及CRP[(31.34±33.68)mg/L]比较差异均有统计学意义(t值分别为-4.289、-5.934,P均＜0.001).结论 CRP及PSI可作为是否重症CAP分级,且CRP可作为PSI评分系统的一个补充,尤其在非老年患者的预后评估中.
目的 探討C反應蛋白(CRP)及肺炎嚴重指數(PSI)在社區穫得性肺炎(CAP)中的變化,以進一步瞭解CRP在CAP嚴重度及預後評估中的作用.方法 我院2009年1月至2011年5月住院CAP患者106例,按PSI評分、是否重癥CAP、是否≥65歲患者分彆分組,測定血清CRP.結果 CRP與PSI評分呈顯著正相關(r=0.453 P=0.000); CAP老年組CRP與PSI評分無相關性,非老年組CRP[(81.70 ±75.63)mg/L]與PSI評分[(78.30±42.63)分]呈顯著正相關(r=0.489,P＜0.001)；CAP重癥組PSI評分[(89.24±36.44)分]及CRP[(106.93±74.76)mg/L]與非重癥組PSI評分[(53.59±35.41)分]及CRP[(31.34±33.68)mg/L]比較差異均有統計學意義(t值分彆為-4.289、-5.934,P均＜0.001).結論 CRP及PSI可作為是否重癥CAP分級,且CRP可作為PSI評分繫統的一箇補充,尤其在非老年患者的預後評估中.
목적 탐토C반응단백(CRP)급폐염엄중지수(PSI)재사구획득성폐염(CAP)중적변화,이진일보료해CRP재CAP엄중도급예후평고중적작용.방법 아원2009년1월지2011년5월주원CAP환자106례,안PSI평분、시부중증CAP、시부≥65세환자분별분조,측정혈청CRP.결과 CRP여PSI평분정현저정상관(r=0.453 P=0.000); CAP노년조CRP여PSI평분무상관성,비노년조CRP[(81.70 ±75.63)mg/L]여PSI평분[(78.30±42.63)분]정현저정상관(r=0.489,P＜0.001)；CAP중증조PSI평분[(89.24±36.44)분]급CRP[(106.93±74.76)mg/L]여비중증조PSI평분[(53.59±35.41)분]급CRP[(31.34±33.68)mg/L]비교차이균유통계학의의(t치분별위-4.289、-5.934,P균＜0.001).결론 CRP급PSI가작위시부중증CAP분급,차CRP가작위PSI평분계통적일개보충,우기재비노년환자적예후평고중.
Objective To explore the changes of serum C-reactive protein(CRP)and pneumonia severity index(PSI)of community-acquired pneumonia(CAP)and further assess the effect of CRP on the severity and prognosis of CAP.Methods One hundred and six cases of patients with CAP hospitalized from January 2009 to May 2011 were retrospectively analyzed.Patients were classified according to different assessment criteria and age(≥65 years old)and serum CRP was detected in all patients.Results CRP was correlated positively with PSI(r =0.453,P ＜ 0.001).CRP and PSI had no correlation in elderly hospitalized patients with CAP,but CRP([81.70 ± 75.63]mg/L)correlated positively with PSI(78.30 ± 42.63)in non-elderly patients(r =0.489,P ＜ 0.001).There was significant difference on PSI(89.24 ± 36.44 vs 53.59 ± 35.41),CRP ([106.93 ±74.76]mg/L vs[31.34 ±33.68]mg/L)between PSI severity group and PSI non-severity group (t =-4.289,-5.934,respectively,P ＜ 0.001).Conclusion Both CRP and PSI can be used to evaluate the severity of community-acquired pneumonia,and CRP can be used as a supplement to PSI scoring system,especially in the assessment of non-elderly patients.
