CAJ | 학술논문

目的观察双侧丘脑底核-脑深部电刺激术( STN - DBS)治疗3例Meige综合征患者的术后长期疗效.方法 3例Meige综合征患者接受双侧脑深部电极刺激术,术中微电极记录确定准确靶点定位,术后进行参数程控.术后1、3、6、12、24个月及最后一次复诊时进行随访,采用BFMDRS评价治疗效果,观察参数变化.结果 3例患者术后症状均得到明显改善,术后1个月时3例患者BFMDRS总评分、运动评分及功能障碍评分均有下降,术后3-6个月3例患者BFMDRS总评分、运动评分及功能障碍评分改善最明显,改善率达到90％以上,6个月后疗效稳定.结论 STN- DBS治疗3例Meige综合征患者效果理想,可以成为治疗Meige综合征的一种选择.
목적 관찰쌍측구뇌저핵-뇌심부전자격술( STN - DBS)치료3례Meige종합정환자적술후장기료효.방법 3례Meige종합정환자접수쌍측뇌심부전겁자격술,술중미전겁기록학정준학파점정위,술후진행삼수정공.술후1、3、6、12、24개월급최후일차복진시진행수방,채용BFMDRS평개치료효과,관찰삼수변화.결과 3례환자술후증상균득도명현개선,술후1개월시3례환자BFMDRS총평분、운동평분급공능장애평분균유하강,술후3-6개월3례환자BFMDRS총평분、운동평분급공능장애평분개선최명현,개선솔체도90％이상,6개월후료효은정.결론 STN- DBS치료3례Meige종합정환자효과이상,가이성위치료Meige종합정적일충선택.
Objective The aim of the study is to determine the clinical outcomes in patients undergoing subthalamic nucleus deep brain stimulation (STN - DBS) for Meige syndrome.Methods Three Meige syndrome patients underwent STN - DBS operation.Preoperative and postoperative ( 1 months,3 months,6months,12 months,24 months and final follow up) Burke Fahn Marsden Dystonia Rating Scale (BFMDRS)were performed on each patient.Modification of parameters was observed.Results The cranio - facial and cranio - cervical dystonia symptoms of three patients were improved by deep brain stimulation.At three months and six months following DBS,the BFMDRS/movement /disability scores were improved significantly.The BFMDRS improved greater than 90％.Therapeutic effects were stable after six months following DBS.Conclusion STN - DBS surgery could be considered as an optional treatment for Meige syndrome.