中国地方病学杂志
中國地方病學雜誌
중국지방병학잡지
CHINESE JOURNAL OF ENDEMIOLOGY
2010年
6期
641-644
,共4页
刘辉%邓晴%李宗文%周浩%王世昌%刘加勇%王金彪%王小明%高本%刘守军%刘运起
劉輝%鄧晴%李宗文%週浩%王世昌%劉加勇%王金彪%王小明%高本%劉守軍%劉運起
류휘%산청%리종문%주호%왕세창%류가용%왕금표%왕소명%고본%류수군%류운기
碘%饮水%动脉粥样硬化
碘%飲水%動脈粥樣硬化
전%음수%동맥죽양경화
Iodine%Drinking%Atherosclerosis
目的 调查2008年山东省地方性水源性高碘病区成人颈动脉粥样硬化患病情况,探讨水源性高碘与颈动脉粥样硬化发生的关系.方法选择山东省郓城县和巨野县作为高碘病区和对照区,以郓城县的大陈楼村、魏垓村、刘一村和二十里铺村为高碘病村,以巨野县的章西村、毕海南村、夏官屯和祁集村为对照村.利用彩超对40岁以上的高碘病区居民299人和对照区居民323人进行颈动脉粥样硬化检查、诊断和记分.结果大陈楼村、魏垓村、刘一村和二十里铺村4个高碘病村成人颈动脉粥样硬化检出率分别为47.1%(33/70)、62.2%(51/82)、67.5%(52/77)和58.6%(41/70);章西村、毕海南村、夏官屯和祁集村4个对照村成人颈动脉粥样硬化检出率分别为40.7%(35/86)、40.8%(31/76)、38.2%(34/89)和37.5%(27/72).高碘病村和对照村成人颈动脉粥样硬化检出率按年龄标准化后分别为45.81%、58.18%、61.63%、55.34%和34.66%、36.25%、43.01%、41.30%,高碘病村的检出率高于对照村(T=26,P＜0.05).高碘病区299人中,检出阳性163人、阴性136人,0分136人、1～3分120人、4～7分43人;对照区323人中,检出阳性122人、阴性201人,0分201人、1～3分87人、4～7分35人.高碘病区与对照区成人颈动脉粥样硬化阳性检出情况及病变严重程度比较,差异有统计学意义(x2值分别为17.54、18.42,P均＜0.01).结论高碘病区成人动脉粥样硬化检出率增高、病变严重程度增大.
目的 調查2008年山東省地方性水源性高碘病區成人頸動脈粥樣硬化患病情況,探討水源性高碘與頸動脈粥樣硬化髮生的關繫.方法選擇山東省鄆城縣和巨野縣作為高碘病區和對照區,以鄆城縣的大陳樓村、魏垓村、劉一村和二十裏鋪村為高碘病村,以巨野縣的章西村、畢海南村、夏官屯和祁集村為對照村.利用綵超對40歲以上的高碘病區居民299人和對照區居民323人進行頸動脈粥樣硬化檢查、診斷和記分.結果大陳樓村、魏垓村、劉一村和二十裏鋪村4箇高碘病村成人頸動脈粥樣硬化檢齣率分彆為47.1%(33/70)、62.2%(51/82)、67.5%(52/77)和58.6%(41/70);章西村、畢海南村、夏官屯和祁集村4箇對照村成人頸動脈粥樣硬化檢齣率分彆為40.7%(35/86)、40.8%(31/76)、38.2%(34/89)和37.5%(27/72).高碘病村和對照村成人頸動脈粥樣硬化檢齣率按年齡標準化後分彆為45.81%、58.18%、61.63%、55.34%和34.66%、36.25%、43.01%、41.30%,高碘病村的檢齣率高于對照村(T=26,P＜0.05).高碘病區299人中,檢齣暘性163人、陰性136人,0分136人、1～3分120人、4～7分43人;對照區323人中,檢齣暘性122人、陰性201人,0分201人、1～3分87人、4～7分35人.高碘病區與對照區成人頸動脈粥樣硬化暘性檢齣情況及病變嚴重程度比較,差異有統計學意義(x2值分彆為17.54、18.42,P均＜0.01).結論高碘病區成人動脈粥樣硬化檢齣率增高、病變嚴重程度增大.
목적 조사2008년산동성지방성수원성고전병구성인경동맥죽양경화환병정황,탐토수원성고전여경동맥죽양경화발생적관계.방법선택산동성운성현화거야현작위고전병구화대조구,이운성현적대진루촌、위해촌、류일촌화이십리포촌위고전병촌,이거야현적장서촌、필해남촌、하관둔화기집촌위대조촌.이용채초대40세이상적고전병구거민299인화대조구거민323인진행경동맥죽양경화검사、진단화기분.결과대진루촌、위해촌、류일촌화이십리포촌4개고전병촌성인경동맥죽양경화검출솔분별위47.1%(33/70)、62.2%(51/82)、67.5%(52/77)화58.6%(41/70);장서촌、필해남촌、하관둔화기집촌4개대조촌성인경동맥죽양경화검출솔분별위40.7%(35/86)、40.8%(31/76)、38.2%(34/89)화37.5%(27/72).고전병촌화대조촌성인경동맥죽양경화검출솔안년령표준화후분별위45.81%、58.18%、61.63%、55.34%화34.66%、36.25%、43.01%、41.30%,고전병촌적검출솔고우대조촌(T=26,P＜0.05).고전병구299인중,검출양성163인、음성136인,0분136인、1～3분120인、4～7분43인;대조구323인중,검출양성122인、음성201인,0분201인、1～3분87인、4～7분35인.고전병구여대조구성인경동맥죽양경화양성검출정황급병변엄중정도비교,차이유통계학의의(x2치분별위17.54、18.42,P균＜0.01).결론고전병구성인동맥죽양경화검출솔증고、병변엄중정도증대.
Objective To survey the prevalence rates of adult carotid atherosclerosis in water-sourceoriginated high iodine area in Shandong province in 2008 and discuss the relationship between water-sourceoriginated high iodine and carotid atherosclerosis occurrence. Methods Yuncheng county was chosen as observation area which included Dachenlou, Weigai, Liuyi and Ershilipu villages. Juye county was chosen as control that included Zhangxi, Bihainan, Xiaguan and Qiji villages. Two hundred and ninety-nine participants aged over 40 from water-source-originated high iodine areas and 323 residents aged over 40 from normal iodine areas were investigated.Portable-type B mode color Doppler was performed to examine the carotid artery of all participants. The adult carotid atherosclerosis was diagnosed and graded through the ultrasonograms. Results The prevalence rates of adult carotid atherosclerosis in the 4 water-source-originated high iodine villages of Dachenlou, Weigai, Liuyi and Ershilipu were 47.1% (33/70) ,62.2% (51/82) ,67.5% (52/77) and 58.6% (41/70), respectively and the prevalence rates of adult carotid atherosclerosis in the 4 normal iodine villages of Zhangxi, Bihainan, Xiaguan and Qiji were 40.7%(35/86),40.8% (31/76),38.2% (34/89) and 37.5% (27/72), respectively. The prevalence rates of adult carotid atherosclerosis standardized by age in the 4 high iodine villages and the 4 normal iodine villages were 45.81% ,58.18% ,61.63%,55.34% and 34.66%,36.25%,43.01% ,41.30%, respectively. The prevalence rates were higher in high iodine villages than that in control villages(T = 26, P ＜ 0.05 ). There were 136 people scored "0", 120 people scored "1 -3",43 people scored "4 - 7", and total 299 people. There were 201 people scored "0", 87 people scored "1 - 3", 35 people scored "4 - 7", and total 323 people. The expected prevalence rates and severity of adult carotid atherosclerosis was significantly different between high iodine area and normal iodine area (x2 = 17.54,18.42, all P ＜ 0.01).Conclusion The prevalence rate and severity of adult atherosclerosis in water-source-originatod high iodine area is higher than that in normal iodine area.
