CAJ | 학술논문

目的探讨神经中轴钙化性假瘤( CAPNON)的影像特征,提高对该病的诊断水平.方法 5例经病理证实的CAPNON患者术前均进行MR检查,其中4例同时行CT检查,2例行DSA检查,1例行SPECT骨扫描.对所有患者的影像资料进行回顾性分析.结果 5例患者年龄为25～60岁,平均(50±11)岁.男4例,女1例.病灶直径1.5～5.0 cm.病灶3例位于颅底,1例位于椎管,1例位于枕颈交界区.CT平扫均呈钙化影.MR平扫,T1WI为等低信号,T2WI中4例为等低信号、1例为高低混杂信号；MR增强扫描,3例周边强化、1例无强化、1例均匀强化.病理上可见钙化组织、纤维上皮组织及黏液样基质.5例周围均无水肿.结论 CAPNON好发于成人男性,神经中轴部位常见,CT以钙化为主,MR以等低信号及周边强化为主,有助于诊断.
목적 탐토신경중축개화성가류( CAPNON)적영상특정,제고대해병적진단수평.방법 5례경병리증실적CAPNON환자술전균진행MR검사,기중4례동시행CT검사,2례행DSA검사,1례행SPECT골소묘.대소유환자적영상자료진행회고성분석.결과 5례환자년령위25～60세,평균(50±11)세.남4례,녀1례.병조직경1.5～5.0 cm.병조3례위우로저,1례위우추관,1례위우침경교계구.CT평소균정개화영.MR평소,T1WI위등저신호,T2WI중4례위등저신호、1례위고저혼잡신호；MR증강소묘,3례주변강화、1례무강화、1례균균강화.병리상가견개화조직、섬유상피조직급점액양기질.5례주위균무수종.결론 CAPNON호발우성인남성,신경중축부위상견,CT이개화위주,MR이등저신호급주변강화위주,유조우진단.
Objective To identify the imaging characteristics of calcifying pseudoneoplasms of the neuraxis (CAPNON) and do literature review.Methods Five patients of pathologically-proved CAPNON underwent preoperative MR examination,among which 4 underwent CT scan,2 underwent DSA examination and 1 underwent SPECT. All imaging data were retrospectively analyzed with the emphasis on imaging characteristics.Results Five patients of CAPNON with the diameter of 1.5 to 5.0 cm were found in five patients ( Male 4 ; Female 1 ; age 25 to 60 years old ).Three lesions were located in the skull base,one was located in the cervical spine and one in the foramen magnum and upper cervical segment. All patients underwent MRI examination and 4 of them also took CT scanning.On plain CT,all lesions showed obvious calcification.On T1WI all masses showed hypointensity,and on T2WI 4 of the lesions showed iso- or hypointensity and 1 heterogeneous signal intensity. On contrast-enhanced MR images, peripheral enhancement was demonstrated in 3 lesions,homogeneous enhancement was found in case and one lesion showed no enhancement. The pathologic analysis indicated that inside the lesions were abundant calcification,fibroepithelial tissue and mucoid matrix and no edema was detected around the lesions.Conclusions CAPNON displayed the predilection to male adults and the neuraxis was the predilection site.Calcification on CT images,hypointensity on MR images and peripheral enhancement will be helpful for the diagnosis of CAPNON,but the final confirmation still needs the pathologic results.