现代检验医学杂志
現代檢驗醫學雜誌
현대검험의학잡지
JOURNAL OF MODERN LABORATORY MEDICINE
2006年
5期
36-38
,共3页
耐甲氧西林金黄色葡萄球菌%甲氧西林敏感金黄色葡萄球菌%氨基糖苷类%耐药基因
耐甲氧西林金黃色葡萄毬菌%甲氧西林敏感金黃色葡萄毬菌%氨基糖苷類%耐藥基因
내갑양서림금황색포도구균%갑양서림민감금황색포도구균%안기당감류%내약기인
目的 比较耐甲氧西林金黄色葡萄球菌(MRSA)和甲氧西林敏感的金黄色葡萄球菌(MSSA)对氨基糖苷类药物耐药性和耐药基因携带的不同.方法 运用K-B法和PCR方法分别对16株MRSA和24株MSSA 4种氨基糖苷药物(丁胺卡那霉素、奈替米星、庆大霉素、妥布霉素)耐药性和氨基糖苷类耐药基因进行检测.结果 MRSA与MSSA对氨基糖苷类药物耐药率分别为93.8%,62.5%,100%,100%和0.0%,0.0%,29.2%,33.3%,三种氨基糖苷类药物耐药基因aac(6')/aph(2")、aph(3')Ⅲ、ant(4',4")携带率分别为68.8%,62.5%,6.3%和29.2%,8.3%,0.0%.结论 MRSA较MSSA对氨基糖苷类药物有着更高的耐药性和耐药基因携带率.MRSA较MSSA对氨基糖苷类药物存在着更为复杂的耐药机制.
目的 比較耐甲氧西林金黃色葡萄毬菌(MRSA)和甲氧西林敏感的金黃色葡萄毬菌(MSSA)對氨基糖苷類藥物耐藥性和耐藥基因攜帶的不同.方法 運用K-B法和PCR方法分彆對16株MRSA和24株MSSA 4種氨基糖苷藥物(丁胺卡那黴素、奈替米星、慶大黴素、妥佈黴素)耐藥性和氨基糖苷類耐藥基因進行檢測.結果 MRSA與MSSA對氨基糖苷類藥物耐藥率分彆為93.8%,62.5%,100%,100%和0.0%,0.0%,29.2%,33.3%,三種氨基糖苷類藥物耐藥基因aac(6')/aph(2")、aph(3')Ⅲ、ant(4',4")攜帶率分彆為68.8%,62.5%,6.3%和29.2%,8.3%,0.0%.結論 MRSA較MSSA對氨基糖苷類藥物有著更高的耐藥性和耐藥基因攜帶率.MRSA較MSSA對氨基糖苷類藥物存在著更為複雜的耐藥機製.
목적 비교내갑양서림금황색포도구균(MRSA)화갑양서림민감적금황색포도구균(MSSA)대안기당감류약물내약성화내약기인휴대적불동.방법 운용K-B법화PCR방법분별대16주MRSA화24주MSSA 4충안기당감약물(정알잡나매소、내체미성、경대매소、타포매소)내약성화안기당감류내약기인진행검측.결과 MRSA여MSSA대안기당감류약물내약솔분별위93.8%,62.5%,100%,100%화0.0%,0.0%,29.2%,33.3%,삼충안기당감류약물내약기인aac(6')/aph(2")、aph(3')Ⅲ、ant(4',4")휴대솔분별위68.8%,62.5%,6.3%화29.2%,8.3%,0.0%.결론 MRSA교MSSA대안기당감류약물유착경고적내약성화내약기인휴대솔.MRSA교MSSA대안기당감류약물존재착경위복잡적내약궤제.
