中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2010年
9期
764-766
,共3页
苑磊%张代富%来晏%姚义安%赵荫涛
苑磊%張代富%來晏%姚義安%趙蔭濤
원뢰%장대부%래안%요의안%조음도
冠心病%代谢综合征%冠脉造影%危险因素
冠心病%代謝綜閤徵%冠脈造影%危險因素
관심병%대사종합정%관맥조영%위험인소
Coronary heart disease%Metabolic syndrome%Coronary angiography%Risk factor
将167例冠心病患者分为代谢综合征(MS)组(68例)和非MS组(99例),结果显示,MS组患者相关代谢指标及冠脉造影结果(多支病变、弥漫性病变、闭塞性病变、Ginsini积分)与非MS组相比差异有统计学意义(均P<0.05).根据危险因子数量分组后,5个危险因子组冠脉三支病变、弥漫性病变、闭塞病变明显高于3个危险因子组,3组Ginsini积分随着危险因子数量增多而增大,3个危险因子组与4个和5个危险因子组有明显差异(P<0.05或P<0.01).多因素逻辑回归分析结果显示肥胖、高血压、糖尿病、高低密度脂蛋白胆固醇、低高密度脂蛋白胆固醇与MS患者的冠心病发病有关(P<0.05或P<0.01).
將167例冠心病患者分為代謝綜閤徵(MS)組(68例)和非MS組(99例),結果顯示,MS組患者相關代謝指標及冠脈造影結果(多支病變、瀰漫性病變、閉塞性病變、Ginsini積分)與非MS組相比差異有統計學意義(均P<0.05).根據危險因子數量分組後,5箇危險因子組冠脈三支病變、瀰漫性病變、閉塞病變明顯高于3箇危險因子組,3組Ginsini積分隨著危險因子數量增多而增大,3箇危險因子組與4箇和5箇危險因子組有明顯差異(P<0.05或P<0.01).多因素邏輯迴歸分析結果顯示肥胖、高血壓、糖尿病、高低密度脂蛋白膽固醇、低高密度脂蛋白膽固醇與MS患者的冠心病髮病有關(P<0.05或P<0.01).
장167례관심병환자분위대사종합정(MS)조(68례)화비MS조(99례),결과현시,MS조환자상관대사지표급관맥조영결과(다지병변、미만성병변、폐새성병변、Ginsini적분)여비MS조상비차이유통계학의의(균P<0.05).근거위험인자수량분조후,5개위험인자조관맥삼지병변、미만성병변、폐새병변명현고우3개위험인자조,3조Ginsini적분수착위험인자수량증다이증대,3개위험인자조여4개화5개위험인자조유명현차이(P<0.05혹P<0.01).다인소라집회귀분석결과현시비반、고혈압、당뇨병、고저밀도지단백담고순、저고밀도지단백담고순여MS환자적관심병발병유관(P<0.05혹P<0.01).
A total of 167 coronary heart disease (CHD) patients were divided into metabolic syndrome (MS) group (68 cases) and non-MS group (99 cases). There were significant differences in the disease-related metabolic indicators and coronary angiography (multivessel lesions, diffuse stenosis, occlusive lesions, Ginsini score) between MS group and non-MS group ( all P<0.05 ). When the patients with MS were divided into 3 groups according to the number of componernts of MS, three lesions, diffuse stenosis, and occlusive lesions were more frequent in five components group compared with three components group. Ginsini points rised with the increased risk factors. There existed differences in Ginsini score between three components group and four, five components group (P<0. 05 or P<0.01 ). Multivariable logistic regression analysis showed that obesity, hypertension,diabetes, high low-density lipoprotein-cholesterol, and low high-density lipoprotein-cholesterol were the predictors of CHD in patients with MS (P<0.05 or P<0.01 ).