中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2011年
3期
228-230
,共3页
赵阳%张祎草%梁静%唐炘
趙暘%張祎草%樑靜%唐炘
조양%장의초%량정%당흔
新生血管性青光眼%危险因素%临床研究
新生血管性青光眼%危險因素%臨床研究
신생혈관성청광안%위험인소%림상연구
neovascular glaucoma%risk factors%case-control study
目的 探讨新生血管性青光眼(Neovascular glaucoma,NVG)发病的危险因素和原发因素.方法 选择2006年1月至2009年12月确诊为新生血管性青光眼的159例(178只眼)门诊或住院患者为病例组,以同期就诊,年龄相差3岁以内,相同性别为匹配条件159例非青光眼患者为对照组,对照组人群所患疾病与青光眼无相关性.首先分析病例组NVG发生的直接病因,进一步通过采集每位患者的年龄、性别、职业、吸烟史、饮酒史、心理应激状况、睡眠情况、糖尿病史、高血压病史、心血管病史、眼部手术史、眼部外伤史、近视史、远视、家族史、眼压、血压、血红蛋白、血沉、血糖、血胆固醇、血甘油三酯数据,分别运用单因素和多因素方法分析以上因素与NVG发生的关系.结果 159例NVG患者直接病因分析发现视网膜静脉阻塞61例61只眼(38.4%),糖尿病视网膜病变54例(34.0%),66只眼(42.5%).单因素分析提示吸烟史、糖尿病史、高血压病史、眼部手术史、眼部外伤史、眼压、血压、血糖、血甘油三酯9种因素在两组间的比较差异具有统计学意义(P＜0.05).进一步将以上因素引进行回归分析见,糖尿病史、高血压史、眼部外伤史、眼压、血糖、血甘油三酯被引入回归方程,6种因素均为NVG发生的危险因素(P＜0.10).结论 视网膜静脉阻塞和糖尿病视网膜病变是NVG发生最主要的病因;糖尿病史、高血压史、眼部外伤史、眼压、血糖、血甘油三酯为NVG发生的危险因素.
目的 探討新生血管性青光眼(Neovascular glaucoma,NVG)髮病的危險因素和原髮因素.方法 選擇2006年1月至2009年12月確診為新生血管性青光眼的159例(178隻眼)門診或住院患者為病例組,以同期就診,年齡相差3歲以內,相同性彆為匹配條件159例非青光眼患者為對照組,對照組人群所患疾病與青光眼無相關性.首先分析病例組NVG髮生的直接病因,進一步通過採集每位患者的年齡、性彆、職業、吸煙史、飲酒史、心理應激狀況、睡眠情況、糖尿病史、高血壓病史、心血管病史、眼部手術史、眼部外傷史、近視史、遠視、傢族史、眼壓、血壓、血紅蛋白、血沉、血糖、血膽固醇、血甘油三酯數據,分彆運用單因素和多因素方法分析以上因素與NVG髮生的關繫.結果 159例NVG患者直接病因分析髮現視網膜靜脈阻塞61例61隻眼(38.4%),糖尿病視網膜病變54例(34.0%),66隻眼(42.5%).單因素分析提示吸煙史、糖尿病史、高血壓病史、眼部手術史、眼部外傷史、眼壓、血壓、血糖、血甘油三酯9種因素在兩組間的比較差異具有統計學意義(P＜0.05).進一步將以上因素引進行迴歸分析見,糖尿病史、高血壓史、眼部外傷史、眼壓、血糖、血甘油三酯被引入迴歸方程,6種因素均為NVG髮生的危險因素(P＜0.10).結論 視網膜靜脈阻塞和糖尿病視網膜病變是NVG髮生最主要的病因;糖尿病史、高血壓史、眼部外傷史、眼壓、血糖、血甘油三酯為NVG髮生的危險因素.
목적 탐토신생혈관성청광안(Neovascular glaucoma,NVG)발병적위험인소화원발인소.방법 선택2006년1월지2009년12월학진위신생혈관성청광안적159례(178지안)문진혹주원환자위병례조,이동기취진,년령상차3세이내,상동성별위필배조건159례비청광안환자위대조조,대조조인군소환질병여청광안무상관성.수선분석병례조NVG발생적직접병인,진일보통과채집매위환자적년령、성별、직업、흡연사、음주사、심리응격상황、수면정황、당뇨병사、고혈압병사、심혈관병사、안부수술사、안부외상사、근시사、원시、가족사、안압、혈압、혈홍단백、혈침、혈당、혈담고순、혈감유삼지수거,분별운용단인소화다인소방법분석이상인소여NVG발생적관계.결과 159례NVG환자직접병인분석발현시망막정맥조새61례61지안(38.4%),당뇨병시망막병변54례(34.0%),66지안(42.5%).단인소분석제시흡연사、당뇨병사、고혈압병사、안부수술사、안부외상사、안압、혈압、혈당、혈감유삼지9충인소재량조간적비교차이구유통계학의의(P＜0.05).진일보장이상인소인진행회귀분석견,당뇨병사、고혈압사、안부외상사、안압、혈당、혈감유삼지피인입회귀방정,6충인소균위NVG발생적위험인소(P＜0.10).결론 시망막정맥조새화당뇨병시망막병변시NVG발생최주요적병인;당뇨병사、고혈압사、안부외상사、안압、혈당、혈감유삼지위NVG발생적위험인소.
Objective To investigate the risk factors and primary factors of neovascular glaucoma.Methods A total of 159 (178 eyes) of patients who admittei in our hospital in January 2006 - December 2009because ofneovascular glaucoma were selected as case group,159 matched patients without glaucoma were as control group.Direct causes of NVG were analyzed in case group.Further,the information of age,sex,occupation,smoking history,drinking history,psychological stress,sleep,diabetes mellitus,hypertension,cardiovascular disease,eye surgery,eye trauma history,history of myopia,hyperopia,family history,intraocular pressure,blood pressure,hemoglobin,ESR,blood glucose,blood cholesterol and triglyceride were collected.Univariate and multivariate methods of analysiswere used to analyze the relationship between these factors and the occurrence of NVG.Results Of all the direct causes of NVG,retinal vein occlusion was found in 61 cases and 61eyes (38.4%),diabetic retinopathy in 54 cases (34.0%) and 66 eyes (42.5%),other lesions in 44 cases (27.7%)and 51 eyes (28.7%).Univariate analysis indicated that the factors of smoking history,diabetes mellitus,hypertension,eye surgery,history of ocular trauma,intraocular pressure,blood pressure,blood sugar,blood triglyceride had statistically significant difference between the two groups (P ＜0.05).The factors of diabetes mellitus,hypertension,history of ocular trauma,intraocular pressure,blood sugar,blood triglyceride were introduced in regression equation.All of them were risk factors to NVG (P ＜0.10).Conclusions Retinal vein occlusion and diabetic retinopathy are the main cause of NVG.Diabetes mellitus,hypertension,history of ocular trauma,intraocular pressure,blood sugar,blood triglyceride are NVG occurred risk factors.
