CAJ | 학술논문

目的:系统评价当前研究PET/CT诊断宫颈癌盆腔及主动脉旁淋巴结转移文献的质量并合并分析其准确性.方法:收集当前研究PET/CT诊断宫颈癌盆腔及主动脉旁淋巴结转移的文献,并根据QUADAS(Quality assessment of diagnostic accumcv studies)质量评价标准评价符合纳入标准的文献的质量,用MetaDisc软件对敏感性、特异性等进行合并分析和异质性检验并绘制SROC曲线.结果:共纳入9篇符合纳入标准的文献,宫颈癌患者346例(3979例淋巴结转移).以淋巴结为单位合并分析:敏感度为0.58[95%可信区间(CI)0.51～0.65],特异度为0.98(95%CI 0.98～0.99),阳性预测值为0.686(0.464～0.852),阴性预测值为0.936(0.833～0.995),阳性似然比为21.5(7.20～64.24),阴性似然比为0.43(0.32～0.58),准确度为0.900(0.75～0.993),AUC值0.7724;以病人为单位合并分析:敏感度为0.54(95%CI 0.45～0.63).特异度为0.86(95%CI 0.98-0.99),阳性预测值为0.725(0.471～0.923).阴性预测值为0.765(0.615～0.886),阳性似然比为4.58(1.86～11.31),阴性似然比为0.52(0.34～0.80),准确度为0.756(0.620～0.0.897),AUC值0.8699.结论:PET/CT对宫颈癌盆腔及主动脉旁淋巴结转移具有中度诊断价值,可为制定治疗计划提供较为可靠的指导意见.
목적:계통평개당전연구PET/CT진단궁경암분강급주동맥방림파결전이문헌적질량병합병분석기준학성.방법:수집당전연구PET/CT진단궁경암분강급주동맥방림파결전이적문헌,병근거QUADAS(Quality assessment of diagnostic accumcv studies)질량평개표준평개부합납입표준적문헌적질량,용MetaDisc연건대민감성、특이성등진행합병분석화이질성검험병회제SROC곡선.결과:공납입9편부합납입표준적문헌,궁경암환자346례(3979례림파결전이).이림파결위단위합병분석:민감도위0.58[95%가신구간(CI)0.51～0.65],특이도위0.98(95%CI 0.98～0.99),양성예측치위0.686(0.464～0.852),음성예측치위0.936(0.833～0.995),양성사연비위21.5(7.20～64.24),음성사연비위0.43(0.32～0.58),준학도위0.900(0.75～0.993),AUC치0.7724;이병인위단위합병분석:민감도위0.54(95%CI 0.45～0.63).특이도위0.86(95%CI 0.98-0.99),양성예측치위0.725(0.471～0.923).음성예측치위0.765(0.615～0.886),양성사연비위4.58(1.86～11.31),음성사연비위0.52(0.34～0.80),준학도위0.756(0.620～0.0.897),AUC치0.8699.결론:PET/CT대궁경암분강급주동맥방림파결전이구유중도진단개치,가위제정치료계화제공교위가고적지도의견.