白血病·淋巴瘤
白血病·淋巴瘤
백혈병·림파류
JOURNAL OF LEUKEMIA & LYMPHOMA
2011年
10期
631-634
,共4页
疱疹病毒4型,人%淋巴瘤,B细胞%老年人
皰疹病毒4型,人%淋巴瘤,B細胞%老年人
포진병독4형,인%림파류,B세포%노년인
Herpesvirus 4,human%Lymphoma,B-cell%Aged
在2008版的WHO分类中EB病毒(EBV)阳性老年人弥漫大B细胞淋巴瘤(DLBCL)作为新的类型被单独特别列出.就其发病机制、病理学特征及鉴别诊断、发现DLBCL中的EBV的方法进行讨论,另外还就DLBCL患者中EBV感染状态潜在的预测和预后价值及对这类肿瘤的治疗策略进行讨论.
在2008版的WHO分類中EB病毒(EBV)暘性老年人瀰漫大B細胞淋巴瘤(DLBCL)作為新的類型被單獨特彆列齣.就其髮病機製、病理學特徵及鑒彆診斷、髮現DLBCL中的EBV的方法進行討論,另外還就DLBCL患者中EBV感染狀態潛在的預測和預後價值及對這類腫瘤的治療策略進行討論.
재2008판적WHO분류중EB병독(EBV)양성노년인미만대B세포림파류(DLBCL)작위신적류형피단독특별렬출.취기발병궤제、병이학특정급감별진단、발현DLBCL중적EBV적방법진행토론,령외환취DLBCL환자중EBV감염상태잠재적예측화예후개치급대저류종류적치료책략진행토론.
Epstein-Barr virus-positive (EBV-positive) diffuse large B-cell lymphoma (DLBCL) of the elderly is a newly described lymphoproliferative disorder recently in the most current WHO classification of tumours of haematopoietic and lymphoid tissues.The objective of this review is to provide a thorough and current summary of the existing knowledge of this subtype of DLBCL. It will review and discuss the pathogenesis behind EBV-driven malignant transformation of B cells,the distinct pathologic characteristics of EBV-positive DLBCL,the potential predictive and prognostic value of EBV tumoral status in patients with DLBCL,and potential strategies for the treatment of this rare entity.
