CAJ | 학술논문

目的探讨99Tcm-二亚乙基三胺五乙酸(99Tcm-DTPA)肾动态显像在上尿路结石患者肾功能评价中的临床价值.方法回顾性分析了346例上尿路结石患者的核素肾动态显像、静脉肾盂造影(IVP)和血尿素氮(BUN)、血清肌酐(SCr)值,并依据总肾肾小球滤过率(GFR)将BUN和SCr结果分成4组进行分析.结果 ①346例肾动态显像患者,总肾GFR与BUN、SCr水平呈明显负相关(r=-0.458,P=0.000;r=-0.542,P=0.000).②4组之间比较,BUN和SCr均存在统计学差异(F=49.23,P=0.000;F=80.66,P=0.000);经最小显著差别法分析,组1与组2之间比较,BUN和SCr均无统计学差异(P=0.119和P=0.088);而其余各组之间比较,BUN和SCr均存在统计学差异(P均＜0.05).③IVP不显影的43只患肾中,经99Tcm-DTPA肾动态显像提示有18只(41.9%)有残余肾功能(GFR≥10 ml/min),平均GFR为(21.89±12.81)ml/min.结论 99Tcm-DTPA肾动态显像能早期评价肾功能,特别是对IVP不显影的患肾功能的评价具有重要临床价值.
목적 탐토99Tcm-이아을기삼알오을산(99Tcm-DTPA)신동태현상재상뇨로결석환자신공능평개중적림상개치.방법 회고성분석료346례상뇨로결석환자적핵소신동태현상、정맥신우조영(IVP)화혈뇨소담(BUN)、혈청기항(SCr)치,병의거총신신소구려과솔(GFR)장BUN화SCr결과분성4조진행분석.결과 ①346례신동태현상환자,총신GFR여BUN、SCr수평정명현부상관(r=-0.458,P=0.000;r=-0.542,P=0.000).②4조지간비교,BUN화SCr균존재통계학차이(F=49.23,P=0.000;F=80.66,P=0.000);경최소현저차별법분석,조1여조2지간비교,BUN화SCr균무통계학차이(P=0.119화P=0.088);이기여각조지간비교,BUN화SCr균존재통계학차이(P균＜0.05).③IVP불현영적43지환신중,경99Tcm-DTPA신동태현상제시유18지(41.9%)유잔여신공능(GFR≥10 ml/min),평균GFR위(21.89±12.81)ml/min.결론 99Tcm-DTPA신동태현상능조기평개신공능,특별시대IVP불현영적환신공능적평개구유중요림상개치.
Objective To explore the clinical value of 99Tcm-DTPA renal dynamic imaging in evaluating renal function of the patients with upper urinary tract calculi. Methods The results of 99Tcm-DTPA renal dynamic imaging, glomerular filtration rate(GFR), intravenous pyelography(IVP), blood urea nitrogen (BUN) and serum creatinine(SCr) in 346 patients with upper urinary tract calculi diseases were analyzed retrospectively. These 346 patients were divided into four groups according to their total GFR value. Results ① The renal dynamic imaging in 346 patients could accurately reflect the function of the two kidneys. GFR was negatively related to the serum BUN and SCr levels (r=-0.458, P=0.000 and r=-0.542, P=0.000). ② The BUN and SCr levels showed significant difference among the four groups(F=49.23,P=0.000 and F=80.66,P=0.000). There were no significant difference of the BUN and SCr levels found between group 1 and group 2 (P=0. 119, P=0.088, respectively), while significant difference of the BUN and SCr levels found among the other groups P＜0.05 for all situations). ③ Forty-three kidneys of the 346 patients were not visualized by IVP, while 18 of them (41.9%) had shown residual function (GFR ≥10ml/min) with 99Tcm-DTPA renal dynamic imaging, the mean GFR was( 21.89±12.81 )ml/min. Conclusion 99Tcm-DTPA renal dynamic imaging is valuable to early evaluate the renal function, especially for the sick renal function in IVP detection failed patients.