国际流行病学传染病学杂志
國際流行病學傳染病學雜誌
국제류행병학전염병학잡지
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY AND INFECTIOUS DISEASE
2010年
4期
253-255
,共3页
疱疹,带状%神经痛%泛昔洛韦%复方甘草酸苷%阿昔洛韦
皰疹,帶狀%神經痛%汎昔洛韋%複方甘草痠苷%阿昔洛韋
포진,대상%신경통%범석락위%복방감초산감%아석락위
Herpes zoster%Neuralgia%Famciclovir%Compound glycyrrhizin%Acyclovir
目的 探讨带状疱疹初期治疗方法与神经痛疗效的关系.方法 将120例带状疱疹患者随机分为3组,A组给予泛昔洛韦,B组给予泛昔洛韦联合复方甘草酸苷,C组给予阿昔洛韦联合复方甘草酸苷,疗程均为7 d,随访1个月.结果 疼痛缓解和消失时间B组最短,与A、C两组比较差异均有统计学意义(P＜0.05),A、C两组相近(P＞0.05).A、B、C三组痊愈率1周时分别为40.0%、65.0%和37.5%,2周时分别为62.5%、90.0%和70.0%,4周时分别为90.0%、100.0%和97.5%,B组与A、C组差异有统计学意义(P＜0.05).结论 本研究中,泛昔洛韦联合复方甘草酸苷治疗初期带状疱疹疼痛疗效最好.
目的 探討帶狀皰疹初期治療方法與神經痛療效的關繫.方法 將120例帶狀皰疹患者隨機分為3組,A組給予汎昔洛韋,B組給予汎昔洛韋聯閤複方甘草痠苷,C組給予阿昔洛韋聯閤複方甘草痠苷,療程均為7 d,隨訪1箇月.結果 疼痛緩解和消失時間B組最短,與A、C兩組比較差異均有統計學意義(P＜0.05),A、C兩組相近(P＞0.05).A、B、C三組痊愈率1週時分彆為40.0%、65.0%和37.5%,2週時分彆為62.5%、90.0%和70.0%,4週時分彆為90.0%、100.0%和97.5%,B組與A、C組差異有統計學意義(P＜0.05).結論 本研究中,汎昔洛韋聯閤複方甘草痠苷治療初期帶狀皰疹疼痛療效最好.
목적 탐토대상포진초기치료방법여신경통료효적관계.방법 장120례대상포진환자수궤분위3조,A조급여범석락위,B조급여범석락위연합복방감초산감,C조급여아석락위연합복방감초산감,료정균위7 d,수방1개월.결과 동통완해화소실시간B조최단,여A、C량조비교차이균유통계학의의(P＜0.05),A、C량조상근(P＞0.05).A、B、C삼조전유솔1주시분별위40.0%、65.0%화37.5%,2주시분별위62.5%、90.0%화70.0%,4주시분별위90.0%、100.0%화97.5%,B조여A、C조차이유통계학의의(P＜0.05).결론 본연구중,범석락위연합복방감초산감치료초기대상포진동통료효최호.
Objective To investigate the relations of initial treatment for herpes zoster and neuralgia effect.Methods 120 patients with herpes zoster were randomly divided into three groups. Group A were given famciclovir,group B were combined with famciclovir and compound glycyrrhizin, group C were combined with acyclovir and compound glycyrrhizin, all the cases were treated for 7 days, and followed up for 1 month. Results The time of pain relief and disappearance in group B were the shortest among three groups, there were statistical differences compared to group A and C ( P ＜0.05), and there was no difference between group A and C ( P ＞0.05). The cure rates after 1 week treatment in group A, B and C were 40.0%, 65.0% and 37.5% respectively; after 2 weeks, the rates were 62.5%, 90.0% and 70.0%; after 4 weeks, the rates were 90.0%, 100.0% and 97.5%, and group B was statistical differences compared with group A and C( P ＜ 0.05). Conclusions The effect of famciclovir combined compound glycyrrhizinis is the best for treating herpes zoster in this study.
