中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2008年
5期
450-452
,共3页
王建民%马景学%王长龄%李素芬%陈桂芬%杨爱琴
王建民%馬景學%王長齡%李素芬%陳桂芬%楊愛琴
왕건민%마경학%왕장령%리소분%진계분%양애금
老年性黄斑变性%眼底血管造影%吲哚青绿%荧光素
老年性黃斑變性%眼底血管造影%吲哚青綠%熒光素
노년성황반변성%안저혈관조영%신타청록%형광소
Age-related macular degeneration%Fundus angiography%Indocyanine green%Fluorescein
目的 探讨眼底荧光素血管造影(fundus fluorescein angiography,FFA)和吲哚青绿血管造影(indocyanine green angiography,ICGA)在老年性黄斑变性(age-related macular degeneration,AMD)患者中的临床应用.方法 对AMD患者375例742只眼的FFA和ICGA检查资料进行分析总结.结果 在所有患者中,萎缩型504只眼(67.9%),渗出型238只眼(32.1%).在同步进行FFA和ICGA检查的渗出型AMD93只眼中,FFA检查发现典型性CNV 14只眼(15.1%),隐匿性CNV 79只眼(84.9%);ICGA检查发现边界清楚的CNV48只眼(51.6%),两者相比差异具有统计学意义(x2=27.97,P＜0.01).ICGA检查发现CNV的供养血管6只眼(6.5%),均位于中心凹旁或中心凹外.在发现边界清楚CNV的48只眼中,中心凹下CNV29只眼(60.4%),中心凹旁CNV 12只眼(25.0%),中心凹外CNV7只眼(14.6%).结论 与FFA相比,ICGA可以更加准确地显示CNV,发现CNV的供养血管,对AMD的临床诊断和治疗具有更重要的指导意义.
目的 探討眼底熒光素血管造影(fundus fluorescein angiography,FFA)和吲哚青綠血管造影(indocyanine green angiography,ICGA)在老年性黃斑變性(age-related macular degeneration,AMD)患者中的臨床應用.方法 對AMD患者375例742隻眼的FFA和ICGA檢查資料進行分析總結.結果 在所有患者中,萎縮型504隻眼(67.9%),滲齣型238隻眼(32.1%).在同步進行FFA和ICGA檢查的滲齣型AMD93隻眼中,FFA檢查髮現典型性CNV 14隻眼(15.1%),隱匿性CNV 79隻眼(84.9%);ICGA檢查髮現邊界清楚的CNV48隻眼(51.6%),兩者相比差異具有統計學意義(x2=27.97,P＜0.01).ICGA檢查髮現CNV的供養血管6隻眼(6.5%),均位于中心凹徬或中心凹外.在髮現邊界清楚CNV的48隻眼中,中心凹下CNV29隻眼(60.4%),中心凹徬CNV 12隻眼(25.0%),中心凹外CNV7隻眼(14.6%).結論 與FFA相比,ICGA可以更加準確地顯示CNV,髮現CNV的供養血管,對AMD的臨床診斷和治療具有更重要的指導意義.
목적 탐토안저형광소혈관조영(fundus fluorescein angiography,FFA)화신타청록혈관조영(indocyanine green angiography,ICGA)재노년성황반변성(age-related macular degeneration,AMD)환자중적림상응용.방법 대AMD환자375례742지안적FFA화ICGA검사자료진행분석총결.결과 재소유환자중,위축형504지안(67.9%),삼출형238지안(32.1%).재동보진행FFA화ICGA검사적삼출형AMD93지안중,FFA검사발현전형성CNV 14지안(15.1%),은닉성CNV 79지안(84.9%);ICGA검사발현변계청초적CNV48지안(51.6%),량자상비차이구유통계학의의(x2=27.97,P＜0.01).ICGA검사발현CNV적공양혈관6지안(6.5%),균위우중심요방혹중심요외.재발현변계청초CNV적48지안중,중심요하CNV29지안(60.4%),중심요방CNV 12지안(25.0%),중심요외CNV7지안(14.6%).결론 여FFA상비,ICGA가이경가준학지현시CNV,발현CNV적공양혈관,대AMD적림상진단화치료구유경중요적지도의의.
Objective To investigate the clinical application of fimdus fluorescein angiography(FFA) and indocyanine green angiography(ICGA)in age-related macular degeneration(AMD). Methods The FFA and ICGA data of 742 eyes of 375 AMD patients were analyzed and summarized.Restflts In all patients, 504 eyes (67.9%) were atrophic AMD and 238 eyes (32.1%)were exudative AMD. Of 93 exudative AMD eyes simultaneously performed FFA and ICGA, 14 eyes (15.1%)with classic CNV and 79 eyes (84.9%) with occult CNV were found by FFA, 48 eyes (51.6%)with clear boundary CNV were found by ICGA, and there was significantly statistical difference (x2=27.97,P＜0.01 )between them. Feeder vessels of CNV were found in 6 eyes(6.5% )by ICGA, and all were juxtafoveal and extrafoveal. Of 48 eyes with clear boundary CNV, 29 eyes (60.4%)with subfoveal CNV, 12 eyes (25.0%)with juxtafoveal CNV and 7 eyes (14.6%)with extrafoveal CNV. Conclusions Compared with FFA, ICGA may show CNV more clearly and the feeder vessel of CNV,and is more important to the clinical diagnosis and treatment of AMD.
