CAJ | 학술논문

代谢综合征(MS)是指以糖尿病、肥胖、血脂异常、高血压等为表现的临床症候群,由世界卫生组织在1998年正式命名.随着对MS研究的不断深入,现在普遍认为MS患者体内存在微炎性反应(microinflammation),并且这种微炎性反应还在进一步加重MS,并促进一些临床并发症的出现,具体表现在胰岛素抵抗的加重、高血压的恶化、动脉粥样硬化或心血管疾病的出现以及慢性肾脏病的进展等.本文就近年来关于MS和微炎性反应关系的研究作一综述.
대사종합정(MS)시지이당뇨병、비반、혈지이상、고혈압등위표현적림상증후군,유세계위생조직재1998년정식명명.수착대MS연구적불단심입,현재보편인위MS환자체내존재미염성반응(microinflammation),병차저충미염성반응환재진일보가중MS,병촉진일사림상병발증적출현,구체표현재이도소저항적가중、고혈압적악화、동맥죽양경화혹심혈관질병적출현이급만성신장병적진전등.본문취근년래관우MS화미염성반응관계적연구작일종술.
Metabolic syndrome (MS) is characteristic of diabetes mellitus,obesity, dyslipidemia and hypertension, which is designated first by World Health Organization (WHO) in 1998. With the deep investigation on MS, it is well known that the abnomalies in blood glucose, weight, lipid and blood pressure are often showed in the same individual,which constitute an entity in clinical practices. Moreover, microinflammarion is considered to exist in patients with MS. It can induce some clinical complications, aggravate the prognosis of MS, insulin resistance and hypertension, accelerate the occurrence of atherosclerosis or cardiovascular diseases as well as progression of chronic kidney disease (CKD). This article reviews the relationship between MS and microinflammation.