中华临床感染病杂志
中華臨床感染病雜誌
중화림상감염병잡지
CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
2008年
5期
277-280
,共4页
肝硬化%自发性细菌性腹膜炎%细菌感染%抗药性%抗菌药物
肝硬化%自髮性細菌性腹膜炎%細菌感染%抗藥性%抗菌藥物
간경화%자발성세균성복막염%세균감염%항약성%항균약물
Liver cirrhosis%Spontaneous bacterial peritonitis%Bacterial infections%Drug resistance%Antibacterial agents
目的 探讨乙型肝炎肝硬化合并自发性细菌性腹膜炎(SBP)患者腹水病原菌的分布及其耐药情况,为临床合理选用抗菌药物提供指导.方法 回顾性分析117例腹水细菌培养阳性的肝硬化合并SBP患者的腹水细菌培养和药物敏感性试验结果.结果 117例腹水细菌培养阳性肝硬化合并SBP患者中,共分离出病原菌117株,其中革兰阴性菌占60.68%(71/117),革兰阳性菌占38.46%(45/117).分离菌株的耐药情况比较严重,特别是大肠埃希菌及葡萄球菌,对多种抗菌药物的耐药率均>60%.结论 乙型肝炎肝硬化合并SBP患者细菌耐药情况比较严重,应根据药物敏感性试验结果合理选用抗菌药物.
目的 探討乙型肝炎肝硬化閤併自髮性細菌性腹膜炎(SBP)患者腹水病原菌的分佈及其耐藥情況,為臨床閤理選用抗菌藥物提供指導.方法 迴顧性分析117例腹水細菌培養暘性的肝硬化閤併SBP患者的腹水細菌培養和藥物敏感性試驗結果.結果 117例腹水細菌培養暘性肝硬化閤併SBP患者中,共分離齣病原菌117株,其中革蘭陰性菌佔60.68%(71/117),革蘭暘性菌佔38.46%(45/117).分離菌株的耐藥情況比較嚴重,特彆是大腸埃希菌及葡萄毬菌,對多種抗菌藥物的耐藥率均>60%.結論 乙型肝炎肝硬化閤併SBP患者細菌耐藥情況比較嚴重,應根據藥物敏感性試驗結果閤理選用抗菌藥物.
목적 탐토을형간염간경화합병자발성세균성복막염(SBP)환자복수병원균적분포급기내약정황,위림상합리선용항균약물제공지도.방법 회고성분석117례복수세균배양양성적간경화합병SBP환자적복수세균배양화약물민감성시험결과.결과 117례복수세균배양양성간경화합병SBP환자중,공분리출병원균117주,기중혁란음성균점60.68%(71/117),혁란양성균점38.46%(45/117).분리균주적내약정황비교엄중,특별시대장애희균급포도구균,대다충항균약물적내약솔균>60%.결론 을형간염간경화합병SBP환자세균내약정황비교엄중,응근거약물민감성시험결과합리선용항균약물.
Objective To investigate distributions and drug resistance of pathogens in cirrhotic ascites comphcated with spontaneous bacterial peritonitis (SBP). Methods Results of bacterial culture and drug sensitivity tests of 117 aacitie specimens from cirrhotic patients with SBP were analyzed retrospectively. Results From the 117 ascitie specimens, 117 bacterial strains were isolated, among which 71 (60.68%)were gram-negative bacteria, 45 (38.46%) were gram-positive bacteria. The isolated strains were highly resistant to antibacterial agents, especially for Escherchia coli and Staphylococcu, the resistances to most antibiotics were above 60%. Conclusions High drug resistances were common for pathogenic bacteria in aacites of liver cirrhosis patients complicated with SBP.
