中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
19期
2897-2898
,共2页
庄见齐%郑晓丹%郑晓辉%王光丽%黄可青
莊見齊%鄭曉丹%鄭曉輝%王光麗%黃可青
장견제%정효단%정효휘%왕광려%황가청
肝炎,乙型,慢性%T淋巴细胞亚群%再激活
肝炎,乙型,慢性%T淋巴細胞亞群%再激活
간염,을형,만성%T림파세포아군%재격활
Hepatitis B,chronic%T-Lymphocyte subsets%Reactivation
目的 探讨乙型肝炎(乙肝)病毒再激活与血T淋巴细胞亚群变化的关系.方法 使用流式细胞仪(流式细胞EPICS XL)检测40例慢性乙肝病毒携带者与35例乙肝病毒再激活患者T淋巴细胞亚群( CD3、CD4、CDs、CD4/CDs)水平.结果 乙肝病毒再激活患者CD3 、CD4及CD4/CDs均显著低于慢性乙肝病毒携带者[(71.31±5.20)％与(68.57±6.10)％、(37.82±4.90)％与(32.12±5.93)％、(1.37±0.28)与(1.18±0.43),均P＜0.05].结论 CD3、CD4低水平及CD4/CDs比例的明显下降可能是引起乙肝病毒再激活的重要原因之一.
目的 探討乙型肝炎(乙肝)病毒再激活與血T淋巴細胞亞群變化的關繫.方法 使用流式細胞儀(流式細胞EPICS XL)檢測40例慢性乙肝病毒攜帶者與35例乙肝病毒再激活患者T淋巴細胞亞群( CD3、CD4、CDs、CD4/CDs)水平.結果 乙肝病毒再激活患者CD3 、CD4及CD4/CDs均顯著低于慢性乙肝病毒攜帶者[(71.31±5.20)％與(68.57±6.10)％、(37.82±4.90)％與(32.12±5.93)％、(1.37±0.28)與(1.18±0.43),均P＜0.05].結論 CD3、CD4低水平及CD4/CDs比例的明顯下降可能是引起乙肝病毒再激活的重要原因之一.
목적 탐토을형간염(을간)병독재격활여혈T림파세포아군변화적관계.방법 사용류식세포의(류식세포EPICS XL)검측40례만성을간병독휴대자여35례을간병독재격활환자T림파세포아군( CD3、CD4、CDs、CD4/CDs)수평.결과 을간병독재격활환자CD3 、CD4급CD4/CDs균현저저우만성을간병독휴대자[(71.31±5.20)％여(68.57±6.10)％、(37.82±4.90)％여(32.12±5.93)％、(1.37±0.28)여(1.18±0.43),균P＜0.05].결론 CD3、CD4저수평급CD4/CDs비례적명현하강가능시인기을간병독재격활적중요원인지일.
Objective To investigate the relationship between hepatitis B virus reactivation and the level of blood T-lymphocyte subsets.Methods T lymphocyte subsets ( CD3,CD4,CDs ),CD4/CDs level of 40 patients with chronic carriers of hepatitis B virus and 35 patients with hepatitis B virus re-activation were detected by Flow cytometry(Epics XL).Results The hepatitis B virus reactivation in patients with CD3,CD4 and CD4/CDs levels were significantly lower than the chronic hepatitis B virus carriers,The difference between the two groups patients was significant[(71.31 ±5.20)％ vs (68.57 ±6.10)％,(37.82 ±4.90)％ vs (32.12 ±5.93)％,(1.37 ±0.28) vs (1.18 ±0.43 ),all P ＜ 0.05].Conclusion The levels of CD3,CD4 and CD4/CD8 ratio were significantly declined,it may be the one important reason of hepatitis B virus reactivation.
