中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2008年
12期
21-23
,共3页
乳腺%囊性病变%囊性增生症
乳腺%囊性病變%囊性增生癥
유선%낭성병변%낭성증생증
Breast%Cystic lesion%Cystic hyperplasia
目的 探讨乳腺囊性病变与囊性增生症的关系及其临床意义.方法 收集近3年来诊治的乳腺囊性病变32例的临床资料,分析其,临床、影像及病理学特点.并另选10例乳腺癌旁2 cm内的病变做对照分析.部分病例行免疫组化检测Calponin、P63、actin、34βE12、S-100了解肌上皮表达情况.结果 32例中乳腺囊性增生症16例、导管扩张症5例、乳汁潴留囊肿4例、粘液囊肿样病变1例、单纯囊肿6例.16例"乳腺囊性增生症"均为良性上皮增生,包括硬化性腺病2例、盲管性腺病1例、腺肌上皮腺病3例、导管内乳头状肿瘤10例(中央型6例,外周型乳头状瘤4例);其中非典型乳头状瘤3例,其肌上皮标记相对减弱或消失.癌旁组织见囊性增生症1例,导管内乳头状瘤病5例.结论 囊性病变是增生症的继发改变,囊性增生症的癌变风险在于部分病例的不典型性增生,尤其是非典型性乳头状增生.故临床病理宜区分非典型性与普通型增生,不宜用囊性增生症术语并视之为癌前病变.
目的 探討乳腺囊性病變與囊性增生癥的關繫及其臨床意義.方法 收集近3年來診治的乳腺囊性病變32例的臨床資料,分析其,臨床、影像及病理學特點.併另選10例乳腺癌徬2 cm內的病變做對照分析.部分病例行免疫組化檢測Calponin、P63、actin、34βE12、S-100瞭解肌上皮錶達情況.結果 32例中乳腺囊性增生癥16例、導管擴張癥5例、乳汁潴留囊腫4例、粘液囊腫樣病變1例、單純囊腫6例.16例"乳腺囊性增生癥"均為良性上皮增生,包括硬化性腺病2例、盲管性腺病1例、腺肌上皮腺病3例、導管內乳頭狀腫瘤10例(中央型6例,外週型乳頭狀瘤4例);其中非典型乳頭狀瘤3例,其肌上皮標記相對減弱或消失.癌徬組織見囊性增生癥1例,導管內乳頭狀瘤病5例.結論 囊性病變是增生癥的繼髮改變,囊性增生癥的癌變風險在于部分病例的不典型性增生,尤其是非典型性乳頭狀增生.故臨床病理宜區分非典型性與普通型增生,不宜用囊性增生癥術語併視之為癌前病變.
목적 탐토유선낭성병변여낭성증생증적관계급기림상의의.방법 수집근3년래진치적유선낭성병변32례적림상자료,분석기,림상、영상급병이학특점.병령선10례유선암방2 cm내적병변주대조분석.부분병례행면역조화검측Calponin、P63、actin、34βE12、S-100료해기상피표체정황.결과 32례중유선낭성증생증16례、도관확장증5례、유즙저류낭종4례、점액낭종양병변1례、단순낭종6례.16례"유선낭성증생증"균위량성상피증생,포괄경화성선병2례、맹관성선병1례、선기상피선병3례、도관내유두상종류10례(중앙형6례,외주형유두상류4례);기중비전형유두상류3례,기기상피표기상대감약혹소실.암방조직견낭성증생증1례,도관내유두상류병5례.결론 낭성병변시증생증적계발개변,낭성증생증적암변풍험재우부분병례적불전형성증생,우기시비전형성유두상증생.고림상병리의구분비전형성여보통형증생,불의용낭성증생증술어병시지위암전병변.
Objective To implore the clinical significance and relationship between breast cystic lesion and cystic hyperpalsia. Methods The data of 32 cases of breast cystic lesion diagnosed and treated in the latest 3 years were collected, and their clinical features, image characteristics, pathological structures were analyzed. Some cases were detected with Calponin, P63, aetin ,3413E12 and S - 100 by immunohistochemical test. Results 16 cases were the breast cystic hyperplasia, 5 cases were mammary ductectasia, 4 cases were galactocele, only one case was mucocele - like lesions and 6 cases were single cyst. The 16 cases with cystic hyperplasia were all benign epithelial proliferation. Including 2 eases with sclerosing adenosis, one case with blunt ductal adenosis, 3 cases were adenomyoepithelial adenosis, 10 cases were intraductal papilloma, 6 cases were central type ,4 cases were peripheral type; and there were 3 cases of atypical papilloma, the myoepithelial markers expressed weaken relatively or negative. 1 case of cystic hyperplasia and 5 cases of papilloma were found in para - carcinoma areas. Condnsion The cystic lesions are the secondary change of hyperplasia and the canceration risk of cystic hyperplasia is ascribed to atypical proliferations in partly cases, especially in atypical papillary hyperplasia. So the clinical and pathological diagnosis should be with the term of atypical proliferation and conventional hyperplasia,and the term of cystic hyperplasia would not be suitable.
