CAJ | 학술논문

目的分析儿童获得性梅毒的临床表现及其治疗方法.方法回顾分析2007年7月至2010年12月诊治的14例儿童获得性梅毒患者的临床资料.结果 14例患者中10例为二期梅毒,早、晚期潜伏梅毒各2例.14例患者均有与现症梅毒患者密切接触史或被成人梅毒患者口内咀嚼食物后喂养史.所有患者血清快速血浆反应素环状卡片试验( RPR)及梅毒螺旋体血凝试验(TPHA)均阳性.其皮损主要发生于口腔黏膜,躯干少见,表现为黏膜白斑和黏膜湿丘疹、皮肤脓疱等.7例患者被误诊为其他皮肤病.结论儿童获得性梅毒临床常被误诊或忽视.有不典型皮疹、尤其是与活动性梅毒患者有密切接触者,应考虑儿童获得梅毒可能.
목적 분석인동획득성매독적림상표현급기치료방법.방법 회고분석2007년7월지2010년12월진치적14례인동획득성매독환자적림상자료.결과 14례환자중10례위이기매독,조、만기잠복매독각2례.14례환자균유여현증매독환자밀절접촉사혹피성인매독환자구내저작식물후위양사.소유환자혈청쾌속혈장반응소배상잡편시험( RPR)급매독라선체혈응시험(TPHA)균양성.기피손주요발생우구강점막,구간소견,표현위점막백반화점막습구진、피부농포등.7례환자피오진위기타피부병.결론인동획득성매독림상상피오진혹홀시.유불전형피진、우기시여활동성매독환자유밀절접촉자,응고필인동획득매독가능.
Objective To analyze the clinical manifestations and treatment of acquired syphilis in children.Methods A retrospective analysis was conducted.The clinical data on 14 patients with acquired syphilis collected from July 2007 to December 2010 were assessed.Results Among the 14 cases,10 were secondary syphilis,2 early latent syphilis,and 2 late latent syphilis.Seven of the patients had been misdiagnosed as other diseases.All the patients had a history of close contact with syphilis patients or having mouth-to-mouth feeding history after chewing food by adult patients with syphilis.Both rapid plasma reagin (RPR) test and Treponema pallidum haemagglutination assay (TPHA) were positive in all the patients.The skin lesions were mainly located in the oral cavity mucosa and rarely in the trunk,which included leukoplakia,mucosal wet papules,and pustules.Conclusions Acquired syphilis in children is often clinically misdiagnosed or ignored.For children presenting with atypical skin rashes,especially for those having close contact with active syphilis patients,acquired syphilis should be suspected.